The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.

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Detalles Bibliográficos
Autores principales: Francis R. G. Amrit, Nikki Naim, Ramesh Ratnappan, Julia Loose, Carter Mason, Laura Steenberge, Brooke T. McClendon, Guoqiang Wang, Monica Driscoll, Judith L. Yanowitz, Arjumand Ghazi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/854db20aa1e64954adf08377385046bf
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Sumario:Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.