The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.

Saved in:
Bibliographic Details
Main Authors: Francis R. G. Amrit, Nikki Naim, Ramesh Ratnappan, Julia Loose, Carter Mason, Laura Steenberge, Brooke T. McClendon, Guoqiang Wang, Monica Driscoll, Judith L. Yanowitz, Arjumand Ghazi
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/854db20aa1e64954adf08377385046bf
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.