The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.

Guardado en:
Detalles Bibliográficos
Autores principales: Francis R. G. Amrit, Nikki Naim, Ramesh Ratnappan, Julia Loose, Carter Mason, Laura Steenberge, Brooke T. McClendon, Guoqiang Wang, Monica Driscoll, Judith L. Yanowitz, Arjumand Ghazi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/854db20aa1e64954adf08377385046bf
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:854db20aa1e64954adf08377385046bf
record_format dspace
spelling oai:doaj.org-article:854db20aa1e64954adf08377385046bf2021-12-02T16:57:20ZThe longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity10.1038/s41467-019-10759-z2041-1723https://doaj.org/article/854db20aa1e64954adf08377385046bf2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10759-zhttps://doaj.org/toc/2041-1723Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.Francis R. G. AmritNikki NaimRamesh RatnappanJulia LooseCarter MasonLaura SteenbergeBrooke T. McClendonGuoqiang WangMonica DriscollJudith L. YanowitzArjumand GhaziNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Francis R. G. Amrit
Nikki Naim
Ramesh Ratnappan
Julia Loose
Carter Mason
Laura Steenberge
Brooke T. McClendon
Guoqiang Wang
Monica Driscoll
Judith L. Yanowitz
Arjumand Ghazi
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
description Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.
format article
author Francis R. G. Amrit
Nikki Naim
Ramesh Ratnappan
Julia Loose
Carter Mason
Laura Steenberge
Brooke T. McClendon
Guoqiang Wang
Monica Driscoll
Judith L. Yanowitz
Arjumand Ghazi
author_facet Francis R. G. Amrit
Nikki Naim
Ramesh Ratnappan
Julia Loose
Carter Mason
Laura Steenberge
Brooke T. McClendon
Guoqiang Wang
Monica Driscoll
Judith L. Yanowitz
Arjumand Ghazi
author_sort Francis R. G. Amrit
title The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_short The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_full The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_fullStr The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_full_unstemmed The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_sort longevity-promoting factor, tcer-1, widely represses stress resistance and innate immunity
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/854db20aa1e64954adf08377385046bf
work_keys_str_mv AT francisrgamrit thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT nikkinaim thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT rameshratnappan thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT julialoose thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT cartermason thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT laurasteenberge thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT brooketmcclendon thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT guoqiangwang thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT monicadriscoll thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT judithlyanowitz thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT arjumandghazi thelongevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT francisrgamrit longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT nikkinaim longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT rameshratnappan longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT julialoose longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT cartermason longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT laurasteenberge longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT brooketmcclendon longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT guoqiangwang longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT monicadriscoll longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT judithlyanowitz longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
AT arjumandghazi longevitypromotingfactortcer1widelyrepressesstressresistanceandinnateimmunity
_version_ 1718382576253534208