The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.
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Nature Portfolio
2019
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oai:doaj.org-article:854db20aa1e64954adf08377385046bf2021-12-02T16:57:20ZThe longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity10.1038/s41467-019-10759-z2041-1723https://doaj.org/article/854db20aa1e64954adf08377385046bf2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10759-zhttps://doaj.org/toc/2041-1723Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.Francis R. G. AmritNikki NaimRamesh RatnappanJulia LooseCarter MasonLaura SteenbergeBrooke T. McClendonGuoqiang WangMonica DriscollJudith L. YanowitzArjumand GhaziNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q |
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Science Q Francis R. G. Amrit Nikki Naim Ramesh Ratnappan Julia Loose Carter Mason Laura Steenberge Brooke T. McClendon Guoqiang Wang Monica Driscoll Judith L. Yanowitz Arjumand Ghazi The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity |
description |
Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors. |
format |
article |
author |
Francis R. G. Amrit Nikki Naim Ramesh Ratnappan Julia Loose Carter Mason Laura Steenberge Brooke T. McClendon Guoqiang Wang Monica Driscoll Judith L. Yanowitz Arjumand Ghazi |
author_facet |
Francis R. G. Amrit Nikki Naim Ramesh Ratnappan Julia Loose Carter Mason Laura Steenberge Brooke T. McClendon Guoqiang Wang Monica Driscoll Judith L. Yanowitz Arjumand Ghazi |
author_sort |
Francis R. G. Amrit |
title |
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity |
title_short |
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity |
title_full |
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity |
title_fullStr |
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity |
title_full_unstemmed |
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity |
title_sort |
longevity-promoting factor, tcer-1, widely represses stress resistance and innate immunity |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/854db20aa1e64954adf08377385046bf |
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