The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.

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Bibliographic Details
Main Authors:	Francis R. G. Amrit, Nikki Naim, Ramesh Ratnappan, Julia Loose, Carter Mason, Laura Steenberge, Brooke T. McClendon, Guoqiang Wang, Monica Driscoll, Judith L. Yanowitz, Arjumand Ghazi
Format:	article
Language:	EN
Published:	Nature Portfolio 2019
Subjects:	Science Q
Online Access:	https://doaj.org/article/854db20aa1e64954adf08377385046bf
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spelling	oai:doaj.org-article:854db20aa1e64954adf08377385046bf2021-12-02T16:57:20ZThe longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity10.1038/s41467-019-10759-z2041-1723https://doaj.org/article/854db20aa1e64954adf08377385046bf2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10759-zhttps://doaj.org/toc/2041-1723Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.Francis R. G. AmritNikki NaimRamesh RatnappanJulia LooseCarter MasonLaura SteenbergeBrooke T. McClendonGuoqiang WangMonica DriscollJudith L. YanowitzArjumand GhaziNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Francis R. G. Amrit Nikki Naim Ramesh Ratnappan Julia Loose Carter Mason Laura Steenberge Brooke T. McClendon Guoqiang Wang Monica Driscoll Judith L. Yanowitz Arjumand Ghazi The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
description	Resistance to stress is often associated with increased longevity. Using the model organism C. elegans the authors here show that TCER-1 enhances lifespan while at the same time increasing sensitivity to a number of biotic and abiotic stressors.
format	article
author	Francis R. G. Amrit Nikki Naim Ramesh Ratnappan Julia Loose Carter Mason Laura Steenberge Brooke T. McClendon Guoqiang Wang Monica Driscoll Judith L. Yanowitz Arjumand Ghazi
author_facet	Francis R. G. Amrit Nikki Naim Ramesh Ratnappan Julia Loose Carter Mason Laura Steenberge Brooke T. McClendon Guoqiang Wang Monica Driscoll Judith L. Yanowitz Arjumand Ghazi
author_sort	Francis R. G. Amrit
title	The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_short	The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_full	The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_fullStr	The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_full_unstemmed	The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
title_sort	longevity-promoting factor, tcer-1, widely represses stress resistance and innate immunity
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/854db20aa1e64954adf08377385046bf
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The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

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