Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa

Ken Ogino,1 Maho Oishi,1 Akio Oishi,1 Satoshi Morooka,1 Masako Sugahara,1 Norimoto Gotoh,1,2 Masafumi Kurimoto,3 Nagahisa Yoshimura1 1Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 2Center for Genomic Medicine, Kyoto University, 3Department of Ophthalm...

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Autores principales:	Ogino K, Oishi M, Oishi A, Morooka S, Sugahara M, Gotoh N, Kurimoto M, Yoshimura N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8550418410bc48ceb594119d54ebc6df
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spelling	oai:doaj.org-article:8550418410bc48ceb594119d54ebc6df2021-12-02T06:46:14ZRadial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa1177-5483https://doaj.org/article/8550418410bc48ceb594119d54ebc6df2015-08-01T00:00:00Zhttp://www.dovepress.com/radial-fundus-autofluorescence-in-the-periphery-in-patients-with-x-lin-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Ken Ogino,1 Maho Oishi,1 Akio Oishi,1 Satoshi Morooka,1 Masako Sugahara,1 Norimoto Gotoh,1,2 Masafumi Kurimoto,3 Nagahisa Yoshimura1 1Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 2Center for Genomic Medicine, Kyoto University, 3Department of Ophthalmology, Kyoto Katsura Hospital, Kyoto, JapanPurpose: To describe the peripheral autofluorescence images and clinical features of patients with retinal dystrophy who showed radial fundus autofluorescence (FAF) at the posterior pole.Methods: The authors retrospectively reviewed pooled wide-field FAF images of 711 patients with retinal dystrophy and 56 family members.Results: Eleven eyes of seven women exhibited radial FAF at the posterior pole. Wide-field FAF showed extension of the radial pattern to the periphery in all eyes except one. One woman showed radial hyper-FAF only in the periphery, not at the posterior pole. These eight individuals were X-linked retinitis pigmentosa patients or carriers. The tapetal-like reflex was not observed in their color fundus photographs. The peripheral visual field showed wedge-shaped restriction in some individuals.Conclusion: Wide-field FAF imaging can depict radial FAF not only at the posterior pole but also in the periphery in X-linked retinitis pigmentosa carriers. The authors therefore agree with previous reports that radial FAF may be a hallmark of X-linked retinitis pigmentosa. Keywords: X-linked retinitis pigmentosa, radial pattern, wide-field fundus autofluorescence, RPGR geneOgino KOishi MOishi AMorooka SSugahara MGotoh NKurimoto MYoshimura NDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1467-1474 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Ogino K Oishi M Oishi A Morooka S Sugahara M Gotoh N Kurimoto M Yoshimura N Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
description	Ken Ogino,1 Maho Oishi,1 Akio Oishi,1 Satoshi Morooka,1 Masako Sugahara,1 Norimoto Gotoh,1,2 Masafumi Kurimoto,3 Nagahisa Yoshimura1 1Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 2Center for Genomic Medicine, Kyoto University, 3Department of Ophthalmology, Kyoto Katsura Hospital, Kyoto, JapanPurpose: To describe the peripheral autofluorescence images and clinical features of patients with retinal dystrophy who showed radial fundus autofluorescence (FAF) at the posterior pole.Methods: The authors retrospectively reviewed pooled wide-field FAF images of 711 patients with retinal dystrophy and 56 family members.Results: Eleven eyes of seven women exhibited radial FAF at the posterior pole. Wide-field FAF showed extension of the radial pattern to the periphery in all eyes except one. One woman showed radial hyper-FAF only in the periphery, not at the posterior pole. These eight individuals were X-linked retinitis pigmentosa patients or carriers. The tapetal-like reflex was not observed in their color fundus photographs. The peripheral visual field showed wedge-shaped restriction in some individuals.Conclusion: Wide-field FAF imaging can depict radial FAF not only at the posterior pole but also in the periphery in X-linked retinitis pigmentosa carriers. The authors therefore agree with previous reports that radial FAF may be a hallmark of X-linked retinitis pigmentosa. Keywords: X-linked retinitis pigmentosa, radial pattern, wide-field fundus autofluorescence, RPGR gene
format	article
author	Ogino K Oishi M Oishi A Morooka S Sugahara M Gotoh N Kurimoto M Yoshimura N
author_facet	Ogino K Oishi M Oishi A Morooka S Sugahara M Gotoh N Kurimoto M Yoshimura N
author_sort	Ogino K
title	Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
title_short	Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
title_full	Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
title_fullStr	Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
title_full_unstemmed	Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
title_sort	radial fundus autofluorescence in the periphery in patients with x-linked retinitis pigmentosa
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/8550418410bc48ceb594119d54ebc6df
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Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa

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