Rapid and robust restoration of breathing long after spinal cord injury
Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitinase ABC induces robust rescue of breathing up to 1....
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Nature Portfolio
2018
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oai:doaj.org-article:855272d6d1de435e917538c553e079202021-12-02T17:31:29ZRapid and robust restoration of breathing long after spinal cord injury10.1038/s41467-018-06937-02041-1723https://doaj.org/article/855272d6d1de435e917538c553e079202018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06937-0https://doaj.org/toc/2041-1723Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitinase ABC induces robust rescue of breathing up to 1.5 years following complete hemidiaphragm paralysis.Philippa M. WarrenStephanie C. SteigerThomas E. DickPeter M. MacFarlaneWarren J. AlilainJerry SilverNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Philippa M. Warren Stephanie C. Steiger Thomas E. Dick Peter M. MacFarlane Warren J. Alilain Jerry Silver Rapid and robust restoration of breathing long after spinal cord injury |
description |
Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitinase ABC induces robust rescue of breathing up to 1.5 years following complete hemidiaphragm paralysis. |
format |
article |
author |
Philippa M. Warren Stephanie C. Steiger Thomas E. Dick Peter M. MacFarlane Warren J. Alilain Jerry Silver |
author_facet |
Philippa M. Warren Stephanie C. Steiger Thomas E. Dick Peter M. MacFarlane Warren J. Alilain Jerry Silver |
author_sort |
Philippa M. Warren |
title |
Rapid and robust restoration of breathing long after spinal cord injury |
title_short |
Rapid and robust restoration of breathing long after spinal cord injury |
title_full |
Rapid and robust restoration of breathing long after spinal cord injury |
title_fullStr |
Rapid and robust restoration of breathing long after spinal cord injury |
title_full_unstemmed |
Rapid and robust restoration of breathing long after spinal cord injury |
title_sort |
rapid and robust restoration of breathing long after spinal cord injury |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/855272d6d1de435e917538c553e07920 |
work_keys_str_mv |
AT philippamwarren rapidandrobustrestorationofbreathinglongafterspinalcordinjury AT stephaniecsteiger rapidandrobustrestorationofbreathinglongafterspinalcordinjury AT thomasedick rapidandrobustrestorationofbreathinglongafterspinalcordinjury AT petermmacfarlane rapidandrobustrestorationofbreathinglongafterspinalcordinjury AT warrenjalilain rapidandrobustrestorationofbreathinglongafterspinalcordinjury AT jerrysilver rapidandrobustrestorationofbreathinglongafterspinalcordinjury |
_version_ |
1718380624626057216 |