Rapid and robust restoration of breathing long after spinal cord injury

Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitinase ABC induces robust rescue of breathing up to 1....

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Autores principales: Philippa M. Warren, Stephanie C. Steiger, Thomas E. Dick, Peter M. MacFarlane, Warren J. Alilain, Jerry Silver
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/855272d6d1de435e917538c553e07920
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spelling oai:doaj.org-article:855272d6d1de435e917538c553e079202021-12-02T17:31:29ZRapid and robust restoration of breathing long after spinal cord injury10.1038/s41467-018-06937-02041-1723https://doaj.org/article/855272d6d1de435e917538c553e079202018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06937-0https://doaj.org/toc/2041-1723Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitinase ABC induces robust rescue of breathing up to 1.5 years following complete hemidiaphragm paralysis.Philippa M. WarrenStephanie C. SteigerThomas E. DickPeter M. MacFarlaneWarren J. AlilainJerry SilverNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Philippa M. Warren
Stephanie C. Steiger
Thomas E. Dick
Peter M. MacFarlane
Warren J. Alilain
Jerry Silver
Rapid and robust restoration of breathing long after spinal cord injury
description Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitinase ABC induces robust rescue of breathing up to 1.5 years following complete hemidiaphragm paralysis.
format article
author Philippa M. Warren
Stephanie C. Steiger
Thomas E. Dick
Peter M. MacFarlane
Warren J. Alilain
Jerry Silver
author_facet Philippa M. Warren
Stephanie C. Steiger
Thomas E. Dick
Peter M. MacFarlane
Warren J. Alilain
Jerry Silver
author_sort Philippa M. Warren
title Rapid and robust restoration of breathing long after spinal cord injury
title_short Rapid and robust restoration of breathing long after spinal cord injury
title_full Rapid and robust restoration of breathing long after spinal cord injury
title_fullStr Rapid and robust restoration of breathing long after spinal cord injury
title_full_unstemmed Rapid and robust restoration of breathing long after spinal cord injury
title_sort rapid and robust restoration of breathing long after spinal cord injury
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/855272d6d1de435e917538c553e07920
work_keys_str_mv AT philippamwarren rapidandrobustrestorationofbreathinglongafterspinalcordinjury
AT stephaniecsteiger rapidandrobustrestorationofbreathinglongafterspinalcordinjury
AT thomasedick rapidandrobustrestorationofbreathinglongafterspinalcordinjury
AT petermmacfarlane rapidandrobustrestorationofbreathinglongafterspinalcordinjury
AT warrenjalilain rapidandrobustrestorationofbreathinglongafterspinalcordinjury
AT jerrysilver rapidandrobustrestorationofbreathinglongafterspinalcordinjury
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