White-opaque switching in natural MTLa/α isolates of Candida albicans: evolutionary implications for roles in host adaptation, pathogenesis, and sex.

Phenotypic transitions play critical roles in host adaptation, virulence, and sexual reproduction in pathogenic fungi. A minority of natural isolates of Candida albicans, which are homozygous at the mating type locus (MTL, a/a or α/α), are known to be able to switch between two distinct cell types:...

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Autores principales: Jing Xie, Li Tao, Clarissa J Nobile, Yaojun Tong, Guobo Guan, Yuan Sun, Chengjun Cao, Aaron D Hernday, Alexander D Johnson, Lixin Zhang, Feng-Yan Bai, Guanghua Huang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/8552ba6072fd4e6693325686041714a9
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