$Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review$
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Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review

Obsessive-compulsive disorder (OCD), a disabling chronic neuropsychiatric disease, entails high economic costs to society and has high morbidity and mortality rates. The first-line treatments for OCD are selective serotonin reuptake inhibitors and cognitive-behavioral therapy. However, this disorder...

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Autores principales:	Lucas Praxedes Chaves, Álef Ribeiro Souza, Ledismar José da Silva, Laura de Lima Crivellaro, Marina Ferreira da Silva
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Revinter Publicações Ltda. 2021
Materias:	obsessive compulsive disorder refractory thermocoagulation neurosurgery Medicine R Surgery RD1-811
Acceso en línea:	https://doaj.org/article/8553eac0cd33439a831fa889f3f609bc
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spelling	oai:doaj.org-article:8553eac0cd33439a831fa889f3f609bc2021-11-27T00:19:21ZThermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review0103-53552359-592210.1055/s-0041-1731013https://doaj.org/article/8553eac0cd33439a831fa889f3f609bc2021-08-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731013https://doaj.org/toc/0103-5355https://doaj.org/toc/2359-5922Obsessive-compulsive disorder (OCD), a disabling chronic neuropsychiatric disease, entails high economic costs to society and has high morbidity and mortality rates. The first-line treatments for OCD are selective serotonin reuptake inhibitors and cognitive-behavioral therapy. However, this disorder has the highest refractory index to noninvasive treatment. Alternatively, ablative thermocoagulation neurosurgical techniques have shown efficacy and few adverse effects. The present systematic review aimed to identify validated protocols to observe the effectiveness of ablative procedures in the treatment of severe and refractory OCD, as well as their possible adverse effects and benefits. This review supports the effectiveness of ablative methods by presenting them as a safe non-experimental therapeutic option for cases of highly-refractory OCD. Additional relevant findings were the improvement in cognitive function, functional capacity, affective orientation, and quality of life, which contribute to the destigmatization of this surgical technique. Further controlled studies may lead to the individualization of recommendations of targets for ablative thermocoagulation.Lucas Praxedes ChavesÁlef Ribeiro SouzaLedismar José da SilvaLaura de Lima CrivellaroMarina Ferreira da SilvaThieme Revinter Publicações Ltda.articleobsessive compulsive disorderrefractorythermocoagulationneurosurgeryMedicineRSurgeryRD1-811ENBrazilian Neurosurgery, Vol 40, Iss 04, Pp e333-e338 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	obsessive compulsive disorder refractory thermocoagulation neurosurgery Medicine R Surgery RD1-811
spellingShingle	obsessive compulsive disorder refractory thermocoagulation neurosurgery Medicine R Surgery RD1-811 Lucas Praxedes Chaves Álef Ribeiro Souza Ledismar José da Silva Laura de Lima Crivellaro Marina Ferreira da Silva Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
description	Obsessive-compulsive disorder (OCD), a disabling chronic neuropsychiatric disease, entails high economic costs to society and has high morbidity and mortality rates. The first-line treatments for OCD are selective serotonin reuptake inhibitors and cognitive-behavioral therapy. However, this disorder has the highest refractory index to noninvasive treatment. Alternatively, ablative thermocoagulation neurosurgical techniques have shown efficacy and few adverse effects. The present systematic review aimed to identify validated protocols to observe the effectiveness of ablative procedures in the treatment of severe and refractory OCD, as well as their possible adverse effects and benefits. This review supports the effectiveness of ablative methods by presenting them as a safe non-experimental therapeutic option for cases of highly-refractory OCD. Additional relevant findings were the improvement in cognitive function, functional capacity, affective orientation, and quality of life, which contribute to the destigmatization of this surgical technique. Further controlled studies may lead to the individualization of recommendations of targets for ablative thermocoagulation.
format	article
author	Lucas Praxedes Chaves Álef Ribeiro Souza Ledismar José da Silva Laura de Lima Crivellaro Marina Ferreira da Silva
author_facet	Lucas Praxedes Chaves Álef Ribeiro Souza Ledismar José da Silva Laura de Lima Crivellaro Marina Ferreira da Silva
author_sort	Lucas Praxedes Chaves
title	Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
title_short	Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
title_full	Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
title_fullStr	Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
title_full_unstemmed	Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
title_sort	thermocoagulation as a surgical approach for the treatment of obsessive-compulsive disorder in refractory patients: systematic review
publisher	Thieme Revinter Publicações Ltda.
publishDate	2021
url	https://doaj.org/article/8553eac0cd33439a831fa889f3f609bc
work_keys_str_mv	AT lucaspraxedeschaves thermocoagulationasasurgicalapproachforthetreatmentofobsessivecompulsivedisorderinrefractorypatientssystematicreview AT alefribeirosouza thermocoagulationasasurgicalapproachforthetreatmentofobsessivecompulsivedisorderinrefractorypatientssystematicreview AT ledismarjosedasilva thermocoagulationasasurgicalapproachforthetreatmentofobsessivecompulsivedisorderinrefractorypatientssystematicreview AT lauradelimacrivellaro thermocoagulationasasurgicalapproachforthetreatmentofobsessivecompulsivedisorderinrefractorypatientssystematicreview AT marinaferreiradasilva thermocoagulationasasurgicalapproachforthetreatmentofobsessivecompulsivedisorderinrefractorypatientssystematicreview
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Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review

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