Expeditious diastereoselective synthesis of elaborated ketones via remote Csp3–H functionalization
C-H activation is a powerful method to form functionalised molecules, but is particularly challenging for unactivated sp3sites. Here the authors report a directing-group-free radical cascade process for converting vinyl azides and carboxylic acids to tetralone derivatives in high diastereoselectivit...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/8554b14d36544c84abbb58a4cb4fdf3a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | C-H activation is a powerful method to form functionalised molecules, but is particularly challenging for unactivated sp3sites. Here the authors report a directing-group-free radical cascade process for converting vinyl azides and carboxylic acids to tetralone derivatives in high diastereoselectivity. |
|---|