Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases

Jiawen Ye, Sizhen Yang, Zihan Wei, Chenhui Cai, Ying Zhang, Hao Qiu, Tongwei Chu Department of Orthopedics, Xinqiao Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Tongwei ChuDepartment of Orthopedics, Xinqiao Hospital, Army Medical University, Shapingba Distr...

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Autores principales:	Ye J, Yang S, Wei Z, Cai C, Zhang Y, Qiu H, Chu T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	lumbar degenerative disease transforaminal lumbar interbody fusion adjacent segment disease risk factors Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8564087b5d284b1ba4738619a3cee895
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spelling	oai:doaj.org-article:8564087b5d284b1ba4738619a3cee8952021-11-16T18:47:50ZIncidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases1178-7074https://doaj.org/article/8564087b5d284b1ba4738619a3cee8952021-11-01T00:00:00Zhttps://www.dovepress.com/incidence-and-risk-factors-for-adjacent-segment-disease-after-transfor-peer-reviewed-fulltext-article-IJGMhttps://doaj.org/toc/1178-7074Jiawen Ye, Sizhen Yang, Zihan Wei, Chenhui Cai, Ying Zhang, Hao Qiu, Tongwei Chu Department of Orthopedics, Xinqiao Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Tongwei ChuDepartment of Orthopedics, Xinqiao Hospital, Army Medical University, Shapingba District, Chongqing, People’s Republic of ChinaTel +86 13708388336Email chtw@sina.comPurpose: To explore the incidence and risk factors for adjacent segment disease (ASD) in patients with lumbar degenerative diseases after transforaminal lumbar interbody fusion (TLIF).Patients and Methods: The clinical data of 1258 patients who underwent transforaminal lumbar interbody fusion (TLIF) for lumbar degenerative diseases in our hospital from January 2011 to December 2017 were retrospectively analyzed. Patients were divided into the ASD group and non-ASD (N-ASD) group, and the incidence of ASD was calculated. We compared age, BMI, comorbidities, surgery-related parameters, and imaging parameters before surgery between the two groups and used univariate analysis and logistic regression analysis to explore the risk factors for ASD.Results: Among the 1258 patients who underwent TLIF due to lumbar degenerative diseases, 65 patients developed ASD and received surgical treatment for it, for an incidence of 5.2%. The average onset time of ASD was 68.3± 25.1 (20– 123) months. Univariate analysis showed that BMI, hypertension, preoperative adjacent segment disc degeneration and preoperative adjacent intervertebral disc height were significantly different between the ASD and N-ASD groups (P< 0.05). Incorporating the above indicators into the logistic regression model, the results showed that BMI and preoperative adjacent intervertebral disc degeneration were risk factors for ASD after TLIF.Conclusion: The incidence of ASD after TLIF in patients with lumbar degenerative disease is approximately 5.2%. High BMI and preoperative adjacent segment disc degeneration are risk factors for ASD after TLIF.Keywords: lumbar degenerative disease, transforaminal lumbar interbody fusion, adjacent segment disease, risk factorsYe JYang SWei ZCai CZhang YQiu HChu TDove Medical Pressarticlelumbar degenerative diseasetransforaminal lumbar interbody fusionadjacent segment diseaserisk factorsMedicine (General)R5-920ENInternational Journal of General Medicine, Vol Volume 14, Pp 8185-8192 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	lumbar degenerative disease transforaminal lumbar interbody fusion adjacent segment disease risk factors Medicine (General) R5-920
spellingShingle	lumbar degenerative disease transforaminal lumbar interbody fusion adjacent segment disease risk factors Medicine (General) R5-920 Ye J Yang S Wei Z Cai C Zhang Y Qiu H Chu T Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
description	Jiawen Ye, Sizhen Yang, Zihan Wei, Chenhui Cai, Ying Zhang, Hao Qiu, Tongwei Chu Department of Orthopedics, Xinqiao Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Tongwei ChuDepartment of Orthopedics, Xinqiao Hospital, Army Medical University, Shapingba District, Chongqing, People’s Republic of ChinaTel +86 13708388336Email chtw@sina.comPurpose: To explore the incidence and risk factors for adjacent segment disease (ASD) in patients with lumbar degenerative diseases after transforaminal lumbar interbody fusion (TLIF).Patients and Methods: The clinical data of 1258 patients who underwent transforaminal lumbar interbody fusion (TLIF) for lumbar degenerative diseases in our hospital from January 2011 to December 2017 were retrospectively analyzed. Patients were divided into the ASD group and non-ASD (N-ASD) group, and the incidence of ASD was calculated. We compared age, BMI, comorbidities, surgery-related parameters, and imaging parameters before surgery between the two groups and used univariate analysis and logistic regression analysis to explore the risk factors for ASD.Results: Among the 1258 patients who underwent TLIF due to lumbar degenerative diseases, 65 patients developed ASD and received surgical treatment for it, for an incidence of 5.2%. The average onset time of ASD was 68.3± 25.1 (20– 123) months. Univariate analysis showed that BMI, hypertension, preoperative adjacent segment disc degeneration and preoperative adjacent intervertebral disc height were significantly different between the ASD and N-ASD groups (P< 0.05). Incorporating the above indicators into the logistic regression model, the results showed that BMI and preoperative adjacent intervertebral disc degeneration were risk factors for ASD after TLIF.Conclusion: The incidence of ASD after TLIF in patients with lumbar degenerative disease is approximately 5.2%. High BMI and preoperative adjacent segment disc degeneration are risk factors for ASD after TLIF.Keywords: lumbar degenerative disease, transforaminal lumbar interbody fusion, adjacent segment disease, risk factors
format	article
author	Ye J Yang S Wei Z Cai C Zhang Y Qiu H Chu T
author_facet	Ye J Yang S Wei Z Cai C Zhang Y Qiu H Chu T
author_sort	Ye J
title	Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
title_short	Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
title_full	Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
title_fullStr	Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
title_full_unstemmed	Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases
title_sort	incidence and risk factors for adjacent segment disease after transforaminal lumbar interbody fusion in patients with lumbar degenerative diseases
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/8564087b5d284b1ba4738619a3cee895
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Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases

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