Treatment outcome and prognostic indices in patients with hyperglycemic emergencies

IU Ezeani,1 A Eregie,2 OS Ogedengbe21Department of Medicine, Federal Medical Centre, Umuahia, Abia State, Nigeria; 2Department of Medicine, University of Benin Teaching Hospital, Benin City, NigeriaObjective: The objective of this study is to assess the treatment outcomes in patients with hyperglyce...

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Autores principales:	Ezeani IU, Eregie A, Ogedengbe OS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/856671e6e079478e80bf6b333490852b
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spelling	oai:doaj.org-article:856671e6e079478e80bf6b333490852b2021-12-02T05:40:11ZTreatment outcome and prognostic indices in patients with hyperglycemic emergencies1178-7007https://doaj.org/article/856671e6e079478e80bf6b333490852b2013-08-01T00:00:00Zhttp://www.dovepress.com/treatment-outcome-and-prognostic-indices-in-patients-with-hyperglycemi-a14069https://doaj.org/toc/1178-7007IU Ezeani,1 A Eregie,2 OS Ogedengbe21Department of Medicine, Federal Medical Centre, Umuahia, Abia State, Nigeria; 2Department of Medicine, University of Benin Teaching Hospital, Benin City, NigeriaObjective: The objective of this study is to assess the treatment outcomes in patients with hyperglycemic emergencies and to ascertain the factors associated with outcome, with emphasis on the determinants of outcome.Method: A total of 105 patients admitted to the Accident and Emergency unit, who fulfilled the criteria for hyperglycemic emergencies, were selected. The information extracted included sociodemographic, clinical, and laboratory data, as well as hospitalization outcome.Results: Of the 105 subjects that participated in the study, hyperosmolar hyperglycemic nonketotic state (HHNK) was seen in 50% (53) of the subjects, while diabetic ketoacidosis (DKA) was seen in 31% (29), normo-osmolar nonketotic hyperglycemic state (NNHS) in 12% (13), and mixed hyperglycemic emergency in 7% (10) of the subjects. The overall mortality rate in this study was 4.8%. Three deaths were recorded in patients with HHNK, while DKA and NNHS each had one death. Three of the deaths occurred within the first 24 hours of admission while the other two were more than 24 hours after admission. The mean (standard deviation) total duration of hospital stay was 24.2 days (SD), and the range of stay was 0.5–88 days.Conclusion: The most common type of hyperglycemic emergency seen in this study was HHNK. Also, the presence of infection, and sex of the study subject, were significant determinants of outcome in this study.Keywords: hyperglycemia, emergency, diabetes mellitus, insulinEzeani IUEregie AOgedengbe OSDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2013, Iss default, Pp 303-307 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Ezeani IU Eregie A Ogedengbe OS Treatment outcome and prognostic indices in patients with hyperglycemic emergencies
description	IU Ezeani,1 A Eregie,2 OS Ogedengbe21Department of Medicine, Federal Medical Centre, Umuahia, Abia State, Nigeria; 2Department of Medicine, University of Benin Teaching Hospital, Benin City, NigeriaObjective: The objective of this study is to assess the treatment outcomes in patients with hyperglycemic emergencies and to ascertain the factors associated with outcome, with emphasis on the determinants of outcome.Method: A total of 105 patients admitted to the Accident and Emergency unit, who fulfilled the criteria for hyperglycemic emergencies, were selected. The information extracted included sociodemographic, clinical, and laboratory data, as well as hospitalization outcome.Results: Of the 105 subjects that participated in the study, hyperosmolar hyperglycemic nonketotic state (HHNK) was seen in 50% (53) of the subjects, while diabetic ketoacidosis (DKA) was seen in 31% (29), normo-osmolar nonketotic hyperglycemic state (NNHS) in 12% (13), and mixed hyperglycemic emergency in 7% (10) of the subjects. The overall mortality rate in this study was 4.8%. Three deaths were recorded in patients with HHNK, while DKA and NNHS each had one death. Three of the deaths occurred within the first 24 hours of admission while the other two were more than 24 hours after admission. The mean (standard deviation) total duration of hospital stay was 24.2 days (SD), and the range of stay was 0.5–88 days.Conclusion: The most common type of hyperglycemic emergency seen in this study was HHNK. Also, the presence of infection, and sex of the study subject, were significant determinants of outcome in this study.Keywords: hyperglycemia, emergency, diabetes mellitus, insulin
format	article
author	Ezeani IU Eregie A Ogedengbe OS
author_facet	Ezeani IU Eregie A Ogedengbe OS
author_sort	Ezeani IU
title	Treatment outcome and prognostic indices in patients with hyperglycemic emergencies
title_short	Treatment outcome and prognostic indices in patients with hyperglycemic emergencies
title_full	Treatment outcome and prognostic indices in patients with hyperglycemic emergencies
title_fullStr	Treatment outcome and prognostic indices in patients with hyperglycemic emergencies
title_full_unstemmed	Treatment outcome and prognostic indices in patients with hyperglycemic emergencies
title_sort	treatment outcome and prognostic indices in patients with hyperglycemic emergencies
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/856671e6e079478e80bf6b333490852b
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Treatment outcome and prognostic indices in patients with hyperglycemic emergencies

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