Mechanical stretch induces hair regeneration through the alternative activation of macrophages

Mechanical stretch induces hair regeneration through the alternative activation of macrophages

Mechanical stimulation is known to affect cell proliferation, differentiation, and regeneration. Here, the authors demonstrate that stretching mouse skin recruits macrophages and polarizes them into M2 cells that facilitate hair regeneration through the release of growth factors, including HGF and I...

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Autores principales: Szu-Ying Chu, Chih-Hung Chou, Hsien-Da Huang, Meng-Hua Yen, Hsiao-Chin Hong, Po-Han Chao, Yu-Hsuan Wang, Po-Yu Chen, Shi-Xin Nian, Yu-Ru Chen, Li-Ying Liou, Yu-Chen Liu, Hui-Mei Chen, Feng-Mao Lin, Yun-Ting Chang, Chih-Chiang Chen, Oscar K. Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/8566efb334e94d97a598b8573cfbba21
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Sumario:Mechanical stimulation is known to affect cell proliferation, differentiation, and regeneration. Here, the authors demonstrate that stretching mouse skin recruits macrophages and polarizes them into M2 cells that facilitate hair regeneration through the release of growth factors, including HGF and IGF-1

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