Mechanical stretch induces hair regeneration through the alternative activation of macrophages

Mechanical stimulation is known to affect cell proliferation, differentiation, and regeneration. Here, the authors demonstrate that stretching mouse skin recruits macrophages and polarizes them into M2 cells that facilitate hair regeneration through the release of growth factors, including HGF and I...

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Autores principales:	Szu-Ying Chu, Chih-Hung Chou, Hsien-Da Huang, Meng-Hua Yen, Hsiao-Chin Hong, Po-Han Chao, Yu-Hsuan Wang, Po-Yu Chen, Shi-Xin Nian, Yu-Ru Chen, Li-Ying Liou, Yu-Chen Liu, Hui-Mei Chen, Feng-Mao Lin, Yun-Ting Chang, Chih-Chiang Chen, Oscar K. Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8566efb334e94d97a598b8573cfbba21
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spelling	oai:doaj.org-article:8566efb334e94d97a598b8573cfbba212021-12-02T16:57:32ZMechanical stretch induces hair regeneration through the alternative activation of macrophages10.1038/s41467-019-09402-82041-1723https://doaj.org/article/8566efb334e94d97a598b8573cfbba212019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09402-8https://doaj.org/toc/2041-1723Mechanical stimulation is known to affect cell proliferation, differentiation, and regeneration. Here, the authors demonstrate that stretching mouse skin recruits macrophages and polarizes them into M2 cells that facilitate hair regeneration through the release of growth factors, including HGF and IGF-1Szu-Ying ChuChih-Hung ChouHsien-Da HuangMeng-Hua YenHsiao-Chin HongPo-Han ChaoYu-Hsuan WangPo-Yu ChenShi-Xin NianYu-Ru ChenLi-Ying LiouYu-Chen LiuHui-Mei ChenFeng-Mao LinYun-Ting ChangChih-Chiang ChenOscar K. LeeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Szu-Ying Chu Chih-Hung Chou Hsien-Da Huang Meng-Hua Yen Hsiao-Chin Hong Po-Han Chao Yu-Hsuan Wang Po-Yu Chen Shi-Xin Nian Yu-Ru Chen Li-Ying Liou Yu-Chen Liu Hui-Mei Chen Feng-Mao Lin Yun-Ting Chang Chih-Chiang Chen Oscar K. Lee Mechanical stretch induces hair regeneration through the alternative activation of macrophages
description	Mechanical stimulation is known to affect cell proliferation, differentiation, and regeneration. Here, the authors demonstrate that stretching mouse skin recruits macrophages and polarizes them into M2 cells that facilitate hair regeneration through the release of growth factors, including HGF and IGF-1
format	article
author	Szu-Ying Chu Chih-Hung Chou Hsien-Da Huang Meng-Hua Yen Hsiao-Chin Hong Po-Han Chao Yu-Hsuan Wang Po-Yu Chen Shi-Xin Nian Yu-Ru Chen Li-Ying Liou Yu-Chen Liu Hui-Mei Chen Feng-Mao Lin Yun-Ting Chang Chih-Chiang Chen Oscar K. Lee
author_facet	Szu-Ying Chu Chih-Hung Chou Hsien-Da Huang Meng-Hua Yen Hsiao-Chin Hong Po-Han Chao Yu-Hsuan Wang Po-Yu Chen Shi-Xin Nian Yu-Ru Chen Li-Ying Liou Yu-Chen Liu Hui-Mei Chen Feng-Mao Lin Yun-Ting Chang Chih-Chiang Chen Oscar K. Lee
author_sort	Szu-Ying Chu
title	Mechanical stretch induces hair regeneration through the alternative activation of macrophages
title_short	Mechanical stretch induces hair regeneration through the alternative activation of macrophages
title_full	Mechanical stretch induces hair regeneration through the alternative activation of macrophages
title_fullStr	Mechanical stretch induces hair regeneration through the alternative activation of macrophages
title_full_unstemmed	Mechanical stretch induces hair regeneration through the alternative activation of macrophages
title_sort	mechanical stretch induces hair regeneration through the alternative activation of macrophages
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8566efb334e94d97a598b8573cfbba21
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Mechanical stretch induces hair regeneration through the alternative activation of macrophages

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