Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy

Noriaki Miyanaga and Hideaki Takagi et al. identify an essential role for migratory dendritic cells in mediating immunotherapy treatment against allergies in mice. They show that submandibular lymph node dendritic cells induce regulatory T cells, and their absence abrogates the effectiveness of immu...

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Autores principales: Noriaki Miyanaga, Hideaki Takagi, Tomofumi Uto, Tomohiro Fukaya, Junta Nasu, Takehito Fukui, Yotaro Nishikawa, Tim Sparwasser, Narantsog Choijookhuu, Yoshitaka Hishikawa, Takeshi Nakamura, Tetsuya Tono, Katsuaki Sato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8572ea05bdf44e4d94b437099a1332ef
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Sumario:Noriaki Miyanaga and Hideaki Takagi et al. identify an essential role for migratory dendritic cells in mediating immunotherapy treatment against allergies in mice. They show that submandibular lymph node dendritic cells induce regulatory T cells, and their absence abrogates the effectiveness of immunotherapy treatment.