Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion

(1) Background: This study aimed to evaluate the etiologies and clinical outcomes of patients with pericardial effusion (PE) treated with echo-guided percutaneous pericardiocentesis. (2) Methods: Between July 2010 and December 2020, a total of 502 patients underwent echo-guided percutaneous pericard...

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Autores principales:	Chun-Ting Shih, Wei-Chieh Lee, Hsiu-Yu Fang, Po-Jui Wu, Yen-Nan Fang, Shaur-Zheng Chong
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	pericardial effusion malignancy pericardiocentesis prognosis metastasis Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/857dc05157eb48ce9ed4c9e4518351a7
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spelling	oai:doaj.org-article:857dc05157eb48ce9ed4c9e4518351a72021-11-25T18:00:22ZOutcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion10.3390/jcdd81101502308-3425https://doaj.org/article/857dc05157eb48ce9ed4c9e4518351a72021-11-01T00:00:00Zhttps://www.mdpi.com/2308-3425/8/11/150https://doaj.org/toc/2308-3425(1) Background: This study aimed to evaluate the etiologies and clinical outcomes of patients with pericardial effusion (PE) treated with echo-guided percutaneous pericardiocentesis. (2) Methods: Between July 2010 and December 2020, a total of 502 patients underwent echo-guided percutaneous pericardiocentesis for PE at our hospital. The reasons for PE were malignancy (N = 277), and non-malignancy (N = 225). The comorbidities, complications, and all-cause mortality were compared between the malignancy and non-malignancy groups. (3) Results: In multivariable Cox regression analyses for 1-year mortality, malignancy related PE, nasopharyngeal and oropharyngeal cancer, and metastatic status were positive predictors. A higher incidence of in-hospital and 1-year mortality were observed in patients with malignancy-related PE than with non-malignancy-related PE. In patients with malignancy-related PE, the Kaplan-Meier curve of 1-year all-cause mortality significantly differed between patients with or without metastasis; however, PE with or without malignant cells did not influence the prognosis. (4) Conclusions: In the patients with large PE requiring percutaneous pericardiocentesis, malignancy-related PE, nasopharyngeal and oropharyngeal cancer, and metastatic status were positive predictors of 1-year mortality. In patients with malignancy, a higher incidence of all-cause mortality was noted in patients with metastasis but did not differ between the groups with and without malignant cells in PE.Chun-Ting ShihWei-Chieh LeeHsiu-Yu FangPo-Jui WuYen-Nan FangShaur-Zheng ChongMDPI AGarticlepericardial effusionmalignancypericardiocentesisprognosismetastasisDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of Cardiovascular Development and Disease, Vol 8, Iss 150, p 150 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	pericardial effusion malignancy pericardiocentesis prognosis metastasis Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	pericardial effusion malignancy pericardiocentesis prognosis metastasis Diseases of the circulatory (Cardiovascular) system RC666-701 Chun-Ting Shih Wei-Chieh Lee Hsiu-Yu Fang Po-Jui Wu Yen-Nan Fang Shaur-Zheng Chong Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
description	(1) Background: This study aimed to evaluate the etiologies and clinical outcomes of patients with pericardial effusion (PE) treated with echo-guided percutaneous pericardiocentesis. (2) Methods: Between July 2010 and December 2020, a total of 502 patients underwent echo-guided percutaneous pericardiocentesis for PE at our hospital. The reasons for PE were malignancy (N = 277), and non-malignancy (N = 225). The comorbidities, complications, and all-cause mortality were compared between the malignancy and non-malignancy groups. (3) Results: In multivariable Cox regression analyses for 1-year mortality, malignancy related PE, nasopharyngeal and oropharyngeal cancer, and metastatic status were positive predictors. A higher incidence of in-hospital and 1-year mortality were observed in patients with malignancy-related PE than with non-malignancy-related PE. In patients with malignancy-related PE, the Kaplan-Meier curve of 1-year all-cause mortality significantly differed between patients with or without metastasis; however, PE with or without malignant cells did not influence the prognosis. (4) Conclusions: In the patients with large PE requiring percutaneous pericardiocentesis, malignancy-related PE, nasopharyngeal and oropharyngeal cancer, and metastatic status were positive predictors of 1-year mortality. In patients with malignancy, a higher incidence of all-cause mortality was noted in patients with metastasis but did not differ between the groups with and without malignant cells in PE.
format	article
author	Chun-Ting Shih Wei-Chieh Lee Hsiu-Yu Fang Po-Jui Wu Yen-Nan Fang Shaur-Zheng Chong
author_facet	Chun-Ting Shih Wei-Chieh Lee Hsiu-Yu Fang Po-Jui Wu Yen-Nan Fang Shaur-Zheng Chong
author_sort	Chun-Ting Shih
title	Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
title_short	Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
title_full	Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
title_fullStr	Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
title_full_unstemmed	Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion
title_sort	outcomes of patients with and without malignancy undergoing percutaneous pericardiocentesis for pericardial effusion
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/857dc05157eb48ce9ed4c9e4518351a7
work_keys_str_mv	AT chuntingshih outcomesofpatientswithandwithoutmalignancyundergoingpercutaneouspericardiocentesisforpericardialeffusion AT weichiehlee outcomesofpatientswithandwithoutmalignancyundergoingpercutaneouspericardiocentesisforpericardialeffusion AT hsiuyufang outcomesofpatientswithandwithoutmalignancyundergoingpercutaneouspericardiocentesisforpericardialeffusion AT pojuiwu outcomesofpatientswithandwithoutmalignancyundergoingpercutaneouspericardiocentesisforpericardialeffusion AT yennanfang outcomesofpatientswithandwithoutmalignancyundergoingpercutaneouspericardiocentesisforpericardialeffusion AT shaurzhengchong outcomesofpatientswithandwithoutmalignancyundergoingpercutaneouspericardiocentesisforpericardialeffusion
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Outcomes of Patients with and without Malignancy Undergoing Percutaneous Pericardiocentesis for Pericardial Effusion

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