In-hospital recurrence in a Chinese large cohort with acute ischemic stroke

Abstract Acute ischemic stroke (AIS) has a high risk of recurrence, particularly in the early stage. The purpose of this study was to assess the frequency and risk factors of in-hospital recurrence in patients with AIS in China. A retrospective analysis was performed of all of the patients with new-...

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Autores principales:	Fan Yu, Xiaolu Liu, Qiong Yang, Yu Fu, Dongsheng Fan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8586292c06ce4967bb04ecf6466c54c1
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spelling	oai:doaj.org-article:8586292c06ce4967bb04ecf6466c54c12021-12-02T15:09:39ZIn-hospital recurrence in a Chinese large cohort with acute ischemic stroke10.1038/s41598-019-51277-82045-2322https://doaj.org/article/8586292c06ce4967bb04ecf6466c54c12019-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-51277-8https://doaj.org/toc/2045-2322Abstract Acute ischemic stroke (AIS) has a high risk of recurrence, particularly in the early stage. The purpose of this study was to assess the frequency and risk factors of in-hospital recurrence in patients with AIS in China. A retrospective analysis was performed of all of the patients with new-onset AIS who were hospitalized in the past three years. Recurrence was defined as a new stroke event, with an interval between the primary and recurrent events greater than 24 hours; other potential causes of neurological deterioration were excluded. The risk factors for recurrence were analyzed using univariate and logistic regression analyses. A total of 1,021 patients were included in this study with a median length of stay of 14 days (interquartile range,11–18). In-hospital recurrence occurred in 58 cases (5.68%), primarily during the first five days of hospitalization. In-hospital recurrence significantly prolonged the hospital stay (P < 0.001), and the in-hospital mortality was also significantly increased (P = 0.006). The independent risk factors for in-hospital recurrence included large artery atherosclerosis, urinary or respiratory infection and abnormal blood glucose, whereas recurrence was less likely to occur in the patients with aphasia. Our study showed that the patients with AIS had a high rate of in-hospital recurrence, and the recurrence mainly occurred in the first five days of the hospital stay. In-hospital recurrence resulted in a prolonged hospital stay and a higher in-hospital mortality rate.Fan YuXiaolu LiuQiong YangYu FuDongsheng FanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fan Yu Xiaolu Liu Qiong Yang Yu Fu Dongsheng Fan In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
description	Abstract Acute ischemic stroke (AIS) has a high risk of recurrence, particularly in the early stage. The purpose of this study was to assess the frequency and risk factors of in-hospital recurrence in patients with AIS in China. A retrospective analysis was performed of all of the patients with new-onset AIS who were hospitalized in the past three years. Recurrence was defined as a new stroke event, with an interval between the primary and recurrent events greater than 24 hours; other potential causes of neurological deterioration were excluded. The risk factors for recurrence were analyzed using univariate and logistic regression analyses. A total of 1,021 patients were included in this study with a median length of stay of 14 days (interquartile range,11–18). In-hospital recurrence occurred in 58 cases (5.68%), primarily during the first five days of hospitalization. In-hospital recurrence significantly prolonged the hospital stay (P < 0.001), and the in-hospital mortality was also significantly increased (P = 0.006). The independent risk factors for in-hospital recurrence included large artery atherosclerosis, urinary or respiratory infection and abnormal blood glucose, whereas recurrence was less likely to occur in the patients with aphasia. Our study showed that the patients with AIS had a high rate of in-hospital recurrence, and the recurrence mainly occurred in the first five days of the hospital stay. In-hospital recurrence resulted in a prolonged hospital stay and a higher in-hospital mortality rate.
format	article
author	Fan Yu Xiaolu Liu Qiong Yang Yu Fu Dongsheng Fan
author_facet	Fan Yu Xiaolu Liu Qiong Yang Yu Fu Dongsheng Fan
author_sort	Fan Yu
title	In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
title_short	In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
title_full	In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
title_fullStr	In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
title_full_unstemmed	In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
title_sort	in-hospital recurrence in a chinese large cohort with acute ischemic stroke
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8586292c06ce4967bb04ecf6466c54c1
work_keys_str_mv	AT fanyu inhospitalrecurrenceinachineselargecohortwithacuteischemicstroke AT xiaoluliu inhospitalrecurrenceinachineselargecohortwithacuteischemicstroke AT qiongyang inhospitalrecurrenceinachineselargecohortwithacuteischemicstroke AT yufu inhospitalrecurrenceinachineselargecohortwithacuteischemicstroke AT dongshengfan inhospitalrecurrenceinachineselargecohortwithacuteischemicstroke
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In-hospital recurrence in a Chinese large cohort with acute ischemic stroke

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