Immunological considerations and challenges for regenerative cellular therapies

In this Review, Petrus-Reurer et al describe the roles of both innate and adaptive immune responses in allogeneic graft rejection, in addition to discuss how such responses are determined by the cellular therapy of interest. They also describe the range of in vitro and in vivo approaches used to exa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sandra Petrus-Reurer, Marco Romano, Sarah Howlett, Joanne Louise Jones, Giovanna Lombardi, Kourosh Saeb-Parsy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/859349b557dc4c4183605d19cd5cdb44
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:859349b557dc4c4183605d19cd5cdb44
record_format	dspace
spelling	oai:doaj.org-article:859349b557dc4c4183605d19cd5cdb442021-12-02T18:02:53ZImmunological considerations and challenges for regenerative cellular therapies10.1038/s42003-021-02237-42399-3642https://doaj.org/article/859349b557dc4c4183605d19cd5cdb442021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02237-4https://doaj.org/toc/2399-3642In this Review, Petrus-Reurer et al describe the roles of both innate and adaptive immune responses in allogeneic graft rejection, in addition to discuss how such responses are determined by the cellular therapy of interest. They also describe the range of in vitro and in vivo approaches used to examine the immunogenicity of cellular therapies and consider potential confounders and strategies that can be employed to ameliorate immune rejection.Sandra Petrus-ReurerMarco RomanoSarah HowlettJoanne Louise JonesGiovanna LombardiKourosh Saeb-ParsyNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Sandra Petrus-Reurer Marco Romano Sarah Howlett Joanne Louise Jones Giovanna Lombardi Kourosh Saeb-Parsy Immunological considerations and challenges for regenerative cellular therapies
description	In this Review, Petrus-Reurer et al describe the roles of both innate and adaptive immune responses in allogeneic graft rejection, in addition to discuss how such responses are determined by the cellular therapy of interest. They also describe the range of in vitro and in vivo approaches used to examine the immunogenicity of cellular therapies and consider potential confounders and strategies that can be employed to ameliorate immune rejection.
format	article
author	Sandra Petrus-Reurer Marco Romano Sarah Howlett Joanne Louise Jones Giovanna Lombardi Kourosh Saeb-Parsy
author_facet	Sandra Petrus-Reurer Marco Romano Sarah Howlett Joanne Louise Jones Giovanna Lombardi Kourosh Saeb-Parsy
author_sort	Sandra Petrus-Reurer
title	Immunological considerations and challenges for regenerative cellular therapies
title_short	Immunological considerations and challenges for regenerative cellular therapies
title_full	Immunological considerations and challenges for regenerative cellular therapies
title_fullStr	Immunological considerations and challenges for regenerative cellular therapies
title_full_unstemmed	Immunological considerations and challenges for regenerative cellular therapies
title_sort	immunological considerations and challenges for regenerative cellular therapies
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/859349b557dc4c4183605d19cd5cdb44
work_keys_str_mv	AT sandrapetrusreurer immunologicalconsiderationsandchallengesforregenerativecellulartherapies AT marcoromano immunologicalconsiderationsandchallengesforregenerativecellulartherapies AT sarahhowlett immunologicalconsiderationsandchallengesforregenerativecellulartherapies AT joannelouisejones immunologicalconsiderationsandchallengesforregenerativecellulartherapies AT giovannalombardi immunologicalconsiderationsandchallengesforregenerativecellulartherapies AT kouroshsaebparsy immunologicalconsiderationsandchallengesforregenerativecellulartherapies
_version_	1718378818751692800

Immunological considerations and challenges for regenerative cellular therapies

Ejemplares similares