Identification and Validation of <italic toggle="yes">Loa loa</italic> Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays
ABSTRACT Immunoassays are currently needed to quantify Loa loa microfilariae (mf). To address this need, we have conducted proteomic and bioinformatic analyses of proteins present in the urine of a Loa mf-infected patient and used this information to identify putative biomarkers produced by L. loa m...
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Main Authors: | Papa M. Drame, Zhaojing Meng, Sasisekhar Bennuru, Jesica A. Herrick, Timothy D. Veenstra, Thomas B. Nutman |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2016
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Online Access: | https://doaj.org/article/85a2e55e0d4c4d7e9c2b4b8de7c856f4 |
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