Microglia modulate stable wakefulness via the thalamic reticular nucleus in mice

Here, the authors show that microglia depletion results in unstable wakefulness and altered levels of ceramide, influencing microglia in the mouse thalamic reticular nucleus (TRN). Stable wakefulness can be restored by activation of the TRN or inhibition of ceramide production in the mouse brain.

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Autores principales: Hanxiao Liu, Xinxing Wang, Lu Chen, Liang Chen, Stella E. Tsirka, Shaoyu Ge, Qiaojie Xiong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/85a4e328c23d4b989f9a8c639753deae
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