Linkage of CD8+ T cell exhaustion with high-fat diet-induced tumourigenesis

Abstract Obesity increases the risk of cancer. Increased levels of hormones (such as oestrogen, insulin, insulin-like growth factor, and leptin), free fatty acid-induced production of reactive oxygen species, an altered intestinal microbiome and chronic inflammation are known to be associated with a...

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Bibliographic Details
Main Authors: Tomonobu Kado, Allah Nawaz, Akiko Takikawa, Isao Usui, Kazuyuki Tobe
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
R
Q
Online Access:https://doaj.org/article/85ab8330adc8478fa09fdf2f9cf97c8e
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