Linkage of CD8+ T cell exhaustion with high-fat diet-induced tumourigenesis
Abstract Obesity increases the risk of cancer. Increased levels of hormones (such as oestrogen, insulin, insulin-like growth factor, and leptin), free fatty acid-induced production of reactive oxygen species, an altered intestinal microbiome and chronic inflammation are known to be associated with a...
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Auteurs principaux: | Tomonobu Kado, Allah Nawaz, Akiko Takikawa, Isao Usui, Kazuyuki Tobe |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/85ab8330adc8478fa09fdf2f9cf97c8e |
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