Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging

T1-hyperintense urine can be an incidental finding on MRI with many potential causes, such as prior gadolinium administration or hematuria. This is the case of a 33-year-old female with a history of sickle cell disease complicated by iron overload secondary to chronic transfusions, who has been on m...

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Autores principales:	Trishae Winters, BS, Carissa M. White, MD
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Deferoxamine MRI Urine T1-hyperintensity Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/85b05ce7952f4a85ab20c1d9bca397de
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spelling	oai:doaj.org-article:85b05ce7952f4a85ab20c1d9bca397de2021-11-30T04:15:06ZDeferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging1930-043310.1016/j.radcr.2021.10.005https://doaj.org/article/85b05ce7952f4a85ab20c1d9bca397de2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1930043321007238https://doaj.org/toc/1930-0433T1-hyperintense urine can be an incidental finding on MRI with many potential causes, such as prior gadolinium administration or hematuria. This is the case of a 33-year-old female with a history of sickle cell disease complicated by iron overload secondary to chronic transfusions, who has been on multiple different iron chelation regimens. Due to persistent iron overload despite various treatments, the patient was started on a new iron chelation regimen that utilized a protocol involving inpatient admission for high dose IV deferoxamine. While admitted for the administration of this regimen, the patient underwent an MRI due to acute on chronic hip pain; this MRI demonstrated an incidental finding of T1-hyperintense urine. There was no evidence found to suggest that this T1-hyperintense urine was caused by prior gadolinium administration, hematuria, or other typical causes of T1-hyperintensity. This incidental finding was thought to have been caused by the usage of deferoxamine; to our knowledge, there is no previous literature discussing this association. Therefore, the findings of this case report demonstrate that this medication is an important item to keep in mind while evaluating the differential diagnosis of T1-hyperintense urine.Trishae Winters, BSCarissa M. White, MDElsevierarticleDeferoxamineMRIUrineT1-hyperintensityMedical physics. Medical radiology. Nuclear medicineR895-920ENRadiology Case Reports, Vol 17, Iss 1, Pp 111-114 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Deferoxamine MRI Urine T1-hyperintensity Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	Deferoxamine MRI Urine T1-hyperintensity Medical physics. Medical radiology. Nuclear medicine R895-920 Trishae Winters, BS Carissa M. White, MD Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging
description	T1-hyperintense urine can be an incidental finding on MRI with many potential causes, such as prior gadolinium administration or hematuria. This is the case of a 33-year-old female with a history of sickle cell disease complicated by iron overload secondary to chronic transfusions, who has been on multiple different iron chelation regimens. Due to persistent iron overload despite various treatments, the patient was started on a new iron chelation regimen that utilized a protocol involving inpatient admission for high dose IV deferoxamine. While admitted for the administration of this regimen, the patient underwent an MRI due to acute on chronic hip pain; this MRI demonstrated an incidental finding of T1-hyperintense urine. There was no evidence found to suggest that this T1-hyperintense urine was caused by prior gadolinium administration, hematuria, or other typical causes of T1-hyperintensity. This incidental finding was thought to have been caused by the usage of deferoxamine; to our knowledge, there is no previous literature discussing this association. Therefore, the findings of this case report demonstrate that this medication is an important item to keep in mind while evaluating the differential diagnosis of T1-hyperintense urine.
format	article
author	Trishae Winters, BS Carissa M. White, MD
author_facet	Trishae Winters, BS Carissa M. White, MD
author_sort	Trishae Winters, BS
title	Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging
title_short	Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging
title_full	Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging
title_fullStr	Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging
title_full_unstemmed	Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging
title_sort	deferoxamine as a potential cause of incidentally found t1-hyperintense urine on magnetic resonance imaging
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/85b05ce7952f4a85ab20c1d9bca397de
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Deferoxamine as a potential cause of incidentally found T1-hyperintense urine on magnetic resonance imaging

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