Three-component radical homo Mannich reaction

Due to the ionic nature of its mechanism, the Mannich reaction can only use non-enolizable aldehydes as substrates. Here, the authors expand the scope of the classical Mannich reaction to enolizable aldehydes by employing a radical process resulting in a streamlined synthesis of γ-amino-carbonyl com...

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Bibliographic Details
Main Authors: Shuai Shi, Wenting Qiu, Pannan Miao, Ruining Li, Xianfeng Lin, Zhankui Sun
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Online Access:https://doaj.org/article/85b17ab32aad4d6a8bd0bf6d8e2bdfaa
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