A novel cochlear measurement that predicts inner-ear malformation

Abstract The A-value used in cochlear duct length (CDL) estimation does not take malformed cochleae into consideration. The objective was to determine the A-value reported in the literature, to assess the accuracy of the A-value measurement and to evaluate a novel cochlear measurement in distinguish...

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Autores principales:	Tawfiq Khurayzi, Fida Almuhawas, Abdulrahman Alsanosi, Yassin Abdelsamad, Úna Doyle, Anandhan Dhanasingh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/85c2d5cf772e4815b45c2cee2babfe29
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spelling	oai:doaj.org-article:85c2d5cf772e4815b45c2cee2babfe292021-12-02T14:23:18ZA novel cochlear measurement that predicts inner-ear malformation10.1038/s41598-021-86741-x2045-2322https://doaj.org/article/85c2d5cf772e4815b45c2cee2babfe292021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86741-xhttps://doaj.org/toc/2045-2322Abstract The A-value used in cochlear duct length (CDL) estimation does not take malformed cochleae into consideration. The objective was to determine the A-value reported in the literature, to assess the accuracy of the A-value measurement and to evaluate a novel cochlear measurement in distinguishing malformed cochlea. High resolution Computer Tomography images in the oblique coronal plane/cochlear view of 74 human temporal bones were analyzed. The A-value and novel C-value measurement were evaluated as predictors of inner ear malformation type. The proximity of the facial nerve to the basal turn was evaluated subjectively. 26 publications report on the A-value; but they do not distinguish normal vs. malformed cochleae. The A-values of the normal cochleae compared to the cochleae with cochlear hypoplasia, incomplete partition (IP) type I, -type II, and -type III were significantly different. The A-value does not predict the C-value. The C-values of the normal cochleae compared to the cochleae with IP type I and IP type III were significantly different. The proximity of the facial nerve to the basal turn did not relate to the type of malformation. The A-value is different in normal vs. malformed cochleae. The novel C-value could be used to predict malformed anatomy, although it does not distinguish all malformation types.Tawfiq KhurayziFida AlmuhawasAbdulrahman AlsanosiYassin AbdelsamadÚna DoyleAnandhan DhanasinghNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tawfiq Khurayzi Fida Almuhawas Abdulrahman Alsanosi Yassin Abdelsamad Úna Doyle Anandhan Dhanasingh A novel cochlear measurement that predicts inner-ear malformation
description	Abstract The A-value used in cochlear duct length (CDL) estimation does not take malformed cochleae into consideration. The objective was to determine the A-value reported in the literature, to assess the accuracy of the A-value measurement and to evaluate a novel cochlear measurement in distinguishing malformed cochlea. High resolution Computer Tomography images in the oblique coronal plane/cochlear view of 74 human temporal bones were analyzed. The A-value and novel C-value measurement were evaluated as predictors of inner ear malformation type. The proximity of the facial nerve to the basal turn was evaluated subjectively. 26 publications report on the A-value; but they do not distinguish normal vs. malformed cochleae. The A-values of the normal cochleae compared to the cochleae with cochlear hypoplasia, incomplete partition (IP) type I, -type II, and -type III were significantly different. The A-value does not predict the C-value. The C-values of the normal cochleae compared to the cochleae with IP type I and IP type III were significantly different. The proximity of the facial nerve to the basal turn did not relate to the type of malformation. The A-value is different in normal vs. malformed cochleae. The novel C-value could be used to predict malformed anatomy, although it does not distinguish all malformation types.
format	article
author	Tawfiq Khurayzi Fida Almuhawas Abdulrahman Alsanosi Yassin Abdelsamad Úna Doyle Anandhan Dhanasingh
author_facet	Tawfiq Khurayzi Fida Almuhawas Abdulrahman Alsanosi Yassin Abdelsamad Úna Doyle Anandhan Dhanasingh
author_sort	Tawfiq Khurayzi
title	A novel cochlear measurement that predicts inner-ear malformation
title_short	A novel cochlear measurement that predicts inner-ear malformation
title_full	A novel cochlear measurement that predicts inner-ear malformation
title_fullStr	A novel cochlear measurement that predicts inner-ear malformation
title_full_unstemmed	A novel cochlear measurement that predicts inner-ear malformation
title_sort	novel cochlear measurement that predicts inner-ear malformation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/85c2d5cf772e4815b45c2cee2babfe29
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A novel cochlear measurement that predicts inner-ear malformation

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