Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins

Renal macrophages (RMs) can be of bone marrow or embryonic origin, but their abundance, fate and metabolic profiles in physiological and pathogenic settings are still unclear. Here the authors show, by characterizing these two RMs in multiple transgenic mouse lines, that they exhibit distinct dynami...

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Autores principales:	Fengming Liu, Shen Dai, Dechun Feng, Zhongnan Qin, Xiao Peng, Siva S. V. P. Sakamuri, Mi Ren, Li Huang, Min Cheng, Kabir E. Mohammad, Ping Qu, Yong Chen, Chunling Zhao, Faliang Zhu, Shujian Liang, Bertal H. Aktas, Xiaofeng Yang, Hong Wang, Prasad V. G. Katakam, David W. Busija, Tracy Fischer, Prasun K. Datta, Jay Rappaport, Bin Gao, Xuebin Qin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/85d4c899ee5a433b885013a54da0c7ad
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spelling	oai:doaj.org-article:85d4c899ee5a433b885013a54da0c7ad2021-12-02T14:41:27ZDistinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins10.1038/s41467-020-16158-z2041-1723https://doaj.org/article/85d4c899ee5a433b885013a54da0c7ad2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16158-zhttps://doaj.org/toc/2041-1723Renal macrophages (RMs) can be of bone marrow or embryonic origin, but their abundance, fate and metabolic profiles in physiological and pathogenic settings are still unclear. Here the authors show, by characterizing these two RMs in multiple transgenic mouse lines, that they exhibit distinct dynamics, homeostasis, immune activity, and metabolic properties.Fengming LiuShen DaiDechun FengZhongnan QinXiao PengSiva S. V. P. SakamuriMi RenLi HuangMin ChengKabir E. MohammadPing QuYong ChenChunling ZhaoFaliang ZhuShujian LiangBertal H. AktasXiaofeng YangHong WangPrasad V. G. KatakamDavid W. BusijaTracy FischerPrasun K. DattaJay RappaportBin GaoXuebin QinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fengming Liu Shen Dai Dechun Feng Zhongnan Qin Xiao Peng Siva S. V. P. Sakamuri Mi Ren Li Huang Min Cheng Kabir E. Mohammad Ping Qu Yong Chen Chunling Zhao Faliang Zhu Shujian Liang Bertal H. Aktas Xiaofeng Yang Hong Wang Prasad V. G. Katakam David W. Busija Tracy Fischer Prasun K. Datta Jay Rappaport Bin Gao Xuebin Qin Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
description	Renal macrophages (RMs) can be of bone marrow or embryonic origin, but their abundance, fate and metabolic profiles in physiological and pathogenic settings are still unclear. Here the authors show, by characterizing these two RMs in multiple transgenic mouse lines, that they exhibit distinct dynamics, homeostasis, immune activity, and metabolic properties.
format	article
author	Fengming Liu Shen Dai Dechun Feng Zhongnan Qin Xiao Peng Siva S. V. P. Sakamuri Mi Ren Li Huang Min Cheng Kabir E. Mohammad Ping Qu Yong Chen Chunling Zhao Faliang Zhu Shujian Liang Bertal H. Aktas Xiaofeng Yang Hong Wang Prasad V. G. Katakam David W. Busija Tracy Fischer Prasun K. Datta Jay Rappaport Bin Gao Xuebin Qin
author_facet	Fengming Liu Shen Dai Dechun Feng Zhongnan Qin Xiao Peng Siva S. V. P. Sakamuri Mi Ren Li Huang Min Cheng Kabir E. Mohammad Ping Qu Yong Chen Chunling Zhao Faliang Zhu Shujian Liang Bertal H. Aktas Xiaofeng Yang Hong Wang Prasad V. G. Katakam David W. Busija Tracy Fischer Prasun K. Datta Jay Rappaport Bin Gao Xuebin Qin
author_sort	Fengming Liu
title	Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
title_short	Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
title_full	Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
title_fullStr	Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
title_full_unstemmed	Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
title_sort	distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/85d4c899ee5a433b885013a54da0c7ad
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Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins

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