Cancer spectrum in TP53-deficient golden Syrian hamsters: A new model for li-fraumeni syndrome
Background: The TP53 tumor suppressor gene is the most commonly mutated gene in human cancers. Humans who inherit mutant TP53 alleles develop a wide range of early onset cancers, a disorder called Li-Fraumeni Syndrome (LFS). Trp53-deficient mice recapitulate most but not all of the cancer phenotypes...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Wolters Kluwer Medknow Publications
2021
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| Accès en ligne: | https://doaj.org/article/85da8c116d8c450bb20e5263e01c9ebc |
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