Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis

Modulation of the cholinergic pathway and spleen function can reduce inflammation with invasive implants. Here, the authors show that non-invasive ultrasound stimulation of the spleen reduces disease severity in a mouse model of inflammatory arthritis, partly via altering B and T cell function.

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Detalles Bibliográficos
Autores principales: Daniel P. Zachs, Sarah J. Offutt, Rachel S. Graham, Yohan Kim, Jerel Mueller, Jennifer L. Auger, Nathaniel J. Schuldt, Claire R. W. Kaiser, Abigail P. Heiller, Raini Dutta, Hongsun Guo, Jamu K. Alford, Bryce A. Binstadt, Hubert H. Lim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/85dd15ea79c645d8ba32290636c10411
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Sumario:Modulation of the cholinergic pathway and spleen function can reduce inflammation with invasive implants. Here, the authors show that non-invasive ultrasound stimulation of the spleen reduces disease severity in a mouse model of inflammatory arthritis, partly via altering B and T cell function.