Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis

Modulation of the cholinergic pathway and spleen function can reduce inflammation with invasive implants. Here, the authors show that non-invasive ultrasound stimulation of the spleen reduces disease severity in a mouse model of inflammatory arthritis, partly via altering B and T cell function.

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Autores principales:	Daniel P. Zachs, Sarah J. Offutt, Rachel S. Graham, Yohan Kim, Jerel Mueller, Jennifer L. Auger, Nathaniel J. Schuldt, Claire R. W. Kaiser, Abigail P. Heiller, Raini Dutta, Hongsun Guo, Jamu K. Alford, Bryce A. Binstadt, Hubert H. Lim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/85dd15ea79c645d8ba32290636c10411
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spelling	oai:doaj.org-article:85dd15ea79c645d8ba32290636c104112021-12-02T16:57:32ZNoninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis10.1038/s41467-019-08721-02041-1723https://doaj.org/article/85dd15ea79c645d8ba32290636c104112019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08721-0https://doaj.org/toc/2041-1723Modulation of the cholinergic pathway and spleen function can reduce inflammation with invasive implants. Here, the authors show that non-invasive ultrasound stimulation of the spleen reduces disease severity in a mouse model of inflammatory arthritis, partly via altering B and T cell function.Daniel P. ZachsSarah J. OffuttRachel S. GrahamYohan KimJerel MuellerJennifer L. AugerNathaniel J. SchuldtClaire R. W. KaiserAbigail P. HeillerRaini DuttaHongsun GuoJamu K. AlfordBryce A. BinstadtHubert H. LimNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniel P. Zachs Sarah J. Offutt Rachel S. Graham Yohan Kim Jerel Mueller Jennifer L. Auger Nathaniel J. Schuldt Claire R. W. Kaiser Abigail P. Heiller Raini Dutta Hongsun Guo Jamu K. Alford Bryce A. Binstadt Hubert H. Lim Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
description	Modulation of the cholinergic pathway and spleen function can reduce inflammation with invasive implants. Here, the authors show that non-invasive ultrasound stimulation of the spleen reduces disease severity in a mouse model of inflammatory arthritis, partly via altering B and T cell function.
format	article
author	Daniel P. Zachs Sarah J. Offutt Rachel S. Graham Yohan Kim Jerel Mueller Jennifer L. Auger Nathaniel J. Schuldt Claire R. W. Kaiser Abigail P. Heiller Raini Dutta Hongsun Guo Jamu K. Alford Bryce A. Binstadt Hubert H. Lim
author_facet	Daniel P. Zachs Sarah J. Offutt Rachel S. Graham Yohan Kim Jerel Mueller Jennifer L. Auger Nathaniel J. Schuldt Claire R. W. Kaiser Abigail P. Heiller Raini Dutta Hongsun Guo Jamu K. Alford Bryce A. Binstadt Hubert H. Lim
author_sort	Daniel P. Zachs
title	Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
title_short	Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
title_full	Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
title_fullStr	Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
title_full_unstemmed	Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
title_sort	noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/85dd15ea79c645d8ba32290636c10411
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Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis

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