Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy

Photosensitizers that  are stable in biological conditions with absorption in the biological spectral window are needed for photodynamic therapy. Here, the authors report on the development of a Ruthenium complex for 1 and 2-photon therapy to address these issues and demonstrate application in vivo....

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Autores principales: Johannes Karges, Shi Kuang, Federica Maschietto, Olivier Blacque, Ilaria Ciofini, Hui Chao, Gilles Gasser
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/85e88f4cede345a9b46288b6648635b9
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spelling oai:doaj.org-article:85e88f4cede345a9b46288b6648635b92021-12-02T16:06:04ZRationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy10.1038/s41467-020-16993-02041-1723https://doaj.org/article/85e88f4cede345a9b46288b6648635b92020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16993-0https://doaj.org/toc/2041-1723Photosensitizers that  are stable in biological conditions with absorption in the biological spectral window are needed for photodynamic therapy. Here, the authors report on the development of a Ruthenium complex for 1 and 2-photon therapy to address these issues and demonstrate application in vivo.Johannes KargesShi KuangFederica MaschiettoOlivier BlacqueIlaria CiofiniHui ChaoGilles GasserNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Johannes Karges
Shi Kuang
Federica Maschietto
Olivier Blacque
Ilaria Ciofini
Hui Chao
Gilles Gasser
Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
description Photosensitizers that  are stable in biological conditions with absorption in the biological spectral window are needed for photodynamic therapy. Here, the authors report on the development of a Ruthenium complex for 1 and 2-photon therapy to address these issues and demonstrate application in vivo.
format article
author Johannes Karges
Shi Kuang
Federica Maschietto
Olivier Blacque
Ilaria Ciofini
Hui Chao
Gilles Gasser
author_facet Johannes Karges
Shi Kuang
Federica Maschietto
Olivier Blacque
Ilaria Ciofini
Hui Chao
Gilles Gasser
author_sort Johannes Karges
title Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
title_short Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
title_full Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
title_fullStr Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
title_full_unstemmed Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
title_sort rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/85e88f4cede345a9b46288b6648635b9
work_keys_str_mv AT johanneskarges rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
AT shikuang rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
AT federicamaschietto rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
AT olivierblacque rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
AT ilariaciofini rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
AT huichao rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
AT gillesgasser rationallydesignedrutheniumcomplexesfor1and2photonphotodynamictherapy
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