Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes

Halogenases are playing an important role as tailoring enzymes in biosynthetic pathways. Flavin-dependent tryptophan halogenases (Trp-FDHs) are among the enzymes that have broad substrate scope and high selectivity.

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Autores principales: Jehyun Jeon, Jaehee Lee, Se-Min Jung, Jae Hong Shin, Woon Ju Song, Mina Rho
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/85eb866c48f147f1b42dc39cc799917b
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spelling oai:doaj.org-article:85eb866c48f147f1b42dc39cc799917b2021-12-02T15:16:36ZGenomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes2379-507710.1128/mSystems.00053-21https://doaj.org/article/85eb866c48f147f1b42dc39cc799917b2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00053-21https://doaj.org/toc/2379-5077 Halogenases are playing an important role as tailoring enzymes in biosynthetic pathways. Flavin-dependent tryptophan halogenases (Trp-FDHs) are among the enzymes that have broad substrate scope and high selectivity.Jehyun JeonJaehee LeeSe-Min JungJae Hong ShinWoon Ju SongMina RhoAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Jehyun Jeon
Jaehee Lee
Se-Min Jung
Jae Hong Shin
Woon Ju Song
Mina Rho
Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
description Halogenases are playing an important role as tailoring enzymes in biosynthetic pathways. Flavin-dependent tryptophan halogenases (Trp-FDHs) are among the enzymes that have broad substrate scope and high selectivity.
format article
author Jehyun Jeon
Jaehee Lee
Se-Min Jung
Jae Hong Shin
Woon Ju Song
Mina Rho
author_facet Jehyun Jeon
Jaehee Lee
Se-Min Jung
Jae Hong Shin
Woon Ju Song
Mina Rho
author_sort Jehyun Jeon
title Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
title_short Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
title_full Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
title_fullStr Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
title_full_unstemmed Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
title_sort genomic determinants encode the reactivity and regioselectivity of flavin-dependent halogenases in bacterial genomes and metagenomes
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/85eb866c48f147f1b42dc39cc799917b
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