Lipid vesicles chaperone an encapsulated RNA aptamer

So far little is known about how encapsulation affects the activity and folding of RNA, which is of interest for understanding the origin of cellular life. Here the authors show that encapsulation of functional RNA in vesicles increases RNA activity and improves RNA folding through a biophysical con...

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Autores principales:	Ranajay Saha, Samuel Verbanic, Irene A. Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/85f05e7c018e4d1eafcd2b6bf9d96533
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spelling	oai:doaj.org-article:85f05e7c018e4d1eafcd2b6bf9d965332021-12-02T13:27:23ZLipid vesicles chaperone an encapsulated RNA aptamer10.1038/s41467-018-04783-82041-1723https://doaj.org/article/85f05e7c018e4d1eafcd2b6bf9d965332018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04783-8https://doaj.org/toc/2041-1723So far little is known about how encapsulation affects the activity and folding of RNA, which is of interest for understanding the origin of cellular life. Here the authors show that encapsulation of functional RNA in vesicles increases RNA activity and improves RNA folding through a biophysical confinement effect.Ranajay SahaSamuel VerbanicIrene A. ChenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ranajay Saha Samuel Verbanic Irene A. Chen Lipid vesicles chaperone an encapsulated RNA aptamer
description	So far little is known about how encapsulation affects the activity and folding of RNA, which is of interest for understanding the origin of cellular life. Here the authors show that encapsulation of functional RNA in vesicles increases RNA activity and improves RNA folding through a biophysical confinement effect.
format	article
author	Ranajay Saha Samuel Verbanic Irene A. Chen
author_facet	Ranajay Saha Samuel Verbanic Irene A. Chen
author_sort	Ranajay Saha
title	Lipid vesicles chaperone an encapsulated RNA aptamer
title_short	Lipid vesicles chaperone an encapsulated RNA aptamer
title_full	Lipid vesicles chaperone an encapsulated RNA aptamer
title_fullStr	Lipid vesicles chaperone an encapsulated RNA aptamer
title_full_unstemmed	Lipid vesicles chaperone an encapsulated RNA aptamer
title_sort	lipid vesicles chaperone an encapsulated rna aptamer
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/85f05e7c018e4d1eafcd2b6bf9d96533
work_keys_str_mv	AT ranajaysaha lipidvesicleschaperoneanencapsulatedrnaaptamer AT samuelverbanic lipidvesicleschaperoneanencapsulatedrnaaptamer AT ireneachen lipidvesicleschaperoneanencapsulatedrnaaptamer
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Lipid vesicles chaperone an encapsulated RNA aptamer

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