Human metallo-β-lactamase enzymes degrade penicillin

Human metallo-β-lactamase enzymes degrade penicillin

Abstract Nonribosomal peptides are assemblages, including antibiotics, of canonical amino acids and other molecules. β-lactam antibiotics act on bacterial cell walls and can be cleaved by β-lactamases. β-lactamase activity in humans has been neglected, even though eighteen enzymes have already been...

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Bibliographic Details
Main Authors: Seydina M. Diene, Lucile Pinault, Vivek Keshri, Nicholas Armstrong, Saber Khelaifia, Eric Chabrière, Gustavo Caetano-Anolles, Philippe Colson, Bernard La Scola, Jean-Marc Rolain, Pierre Pontarotti, Didier Raoult
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/85f64b16e26b4baca5d5358296d9896c
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https://doaj.org/article/85f64b16e26b4baca5d5358296d9896c

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