Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.

<h4>Background</h4>Depression causes a large burden of disease worldwide. Effective prevention has the potential to reduce that burden considerably. This study aimed to investigate the cost-effectiveness of minimal contact psychotherapy, based on Lewinsohn's 'Coping with depres...

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Autores principales:	Matthijs van den Berg, Filip Smit, Theo Vos, Pieter H M van Baal
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/85f85d2f12e4442a9fb4eac8962a5d24
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spelling	oai:doaj.org-article:85f85d2f12e4442a9fb4eac8962a5d242021-12-02T20:11:44ZCost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.1932-620310.1371/journal.pone.0022884https://doaj.org/article/85f85d2f12e4442a9fb4eac8962a5d242011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21853053/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Depression causes a large burden of disease worldwide. Effective prevention has the potential to reduce that burden considerably. This study aimed to investigate the cost-effectiveness of minimal contact psychotherapy, based on Lewinsohn's 'Coping with depression' course, targeted at opportunistically screened individuals with sub-threshold depression.<h4>Methods and results</h4>Using a Markov model, future health effects and costs of an intervention scenario and a current practice scenario were estimated. The time horizon was five years. Incremental cost-effectiveness ratios were expressed in euro per Disability Adjusted Life Year (DALY) averted. Probabilistic sensitivity analysis was employed to study the effect of uncertainty in the model parameters. From the health care perspective the incremental cost-effectiveness ratio was € 1,400 per DALY, and from the societal perspective the intervention was cost-saving. Although the estimated incremental costs and effects were surrounded with large uncertainty, given a willingness to pay of € 20,000 per DALY, the probability that the intervention is cost-effective was around 80%.<h4>Conclusion</h4>This modelling study showed that opportunistic screening in primary care for sub-threshold depression in combination with minimal contact psychotherapy may be cost-effective in the prevention of major depression.Matthijs van den BergFilip SmitTheo VosPieter H M van BaalPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 8, p e22884 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Matthijs van den Berg Filip Smit Theo Vos Pieter H M van Baal Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
description	<h4>Background</h4>Depression causes a large burden of disease worldwide. Effective prevention has the potential to reduce that burden considerably. This study aimed to investigate the cost-effectiveness of minimal contact psychotherapy, based on Lewinsohn's 'Coping with depression' course, targeted at opportunistically screened individuals with sub-threshold depression.<h4>Methods and results</h4>Using a Markov model, future health effects and costs of an intervention scenario and a current practice scenario were estimated. The time horizon was five years. Incremental cost-effectiveness ratios were expressed in euro per Disability Adjusted Life Year (DALY) averted. Probabilistic sensitivity analysis was employed to study the effect of uncertainty in the model parameters. From the health care perspective the incremental cost-effectiveness ratio was € 1,400 per DALY, and from the societal perspective the intervention was cost-saving. Although the estimated incremental costs and effects were surrounded with large uncertainty, given a willingness to pay of € 20,000 per DALY, the probability that the intervention is cost-effective was around 80%.<h4>Conclusion</h4>This modelling study showed that opportunistic screening in primary care for sub-threshold depression in combination with minimal contact psychotherapy may be cost-effective in the prevention of major depression.
format	article
author	Matthijs van den Berg Filip Smit Theo Vos Pieter H M van Baal
author_facet	Matthijs van den Berg Filip Smit Theo Vos Pieter H M van Baal
author_sort	Matthijs van den Berg
title	Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
title_short	Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
title_full	Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
title_fullStr	Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
title_full_unstemmed	Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
title_sort	cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/85f85d2f12e4442a9fb4eac8962a5d24
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Cost-effectiveness of opportunistic screening and minimal contact psychotherapy to prevent depression in primary care patients.

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