Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups

Background. Processes of antioxidant protection in different ethnicities, living in the same geographical conditions, are of undoubted scientific interest. The ratio of activity of oxidative processes and antioxidant components not only reflects, but also largely determines the metabolism and adapti...

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Autores principales:	N. A. Kurashova, E. A. Kudeyarova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	adolescents reproductive health lipoperoxidation antioxidants Science Q
Acceso en línea:	https://doaj.org/article/85fa27e16778423f89b85b29f3a4a7eb
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spelling	oai:doaj.org-article:85fa27e16778423f89b85b29f3a4a7eb2021-11-23T06:14:41ZPro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups2541-94202587-959610.29413/ABS.2018-3.6.3https://doaj.org/article/85fa27e16778423f89b85b29f3a4a7eb2019-01-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1877https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. Processes of antioxidant protection in different ethnicities, living in the same geographical conditions, are of undoubted scientific interest. The ratio of activity of oxidative processes and antioxidant components not only reflects, but also largely determines the metabolism and adaptive capabilities of the organism. The key issue in understanding the regulatory and adaptive role of lipid peroxidation reactions in the body is the idea of the existence of a certain balance with the antioxidant defense system.Aims: to study the features of the system of lipid peroxidation and antioxidant protection in adolescents of different ethnicities, living in Eastern Siberia.Materials and methods. Parameters of lipid peroxidation and antioxidant protection were determined in the blood serum by spectrophotometric methods.Results. We found that adolescent Buryat boys had statistically significant decrease in primary and secondary products of lipid peroxidation: ketodienes and conjugated trienes, malondialdehyde, and components of antioxidant protection: retinol, α-tocopherol, the level of total antioxidant activity of blood and reduced glutathione, in comparison with Caucasian adolescents. In Caucasian adolescents with endocrine disorders, there was a statistically significant increase in the level of ketodienes and conjugated trienes, as well as the activity of superoxide dismutase against the background of a decrease of reduced glutathione, tocopherol, and retinol. We revealed a significant increase in the concentration of ketodienes and conjugated trienes and a decrease of the oxidized glutathione in adolescents with endocrine disorders in comparison with healthy adolescents of Buryat ethnicity.Conclusions. Studying of the processes of lipid peroxidation and antioxidant system of the organism can be used as an additional criterion for complex examination of practically healthy adolescents, which significantly enhance the representation about the adaptation possibilities of the organism to external conditions and can become a basis for effective examination of reproductive health in the future.N. A. KurashovaE. A. KudeyarovaScientific Сentre for Family Health and Human Reproduction Problemsarticleadolescentsreproductive healthlipoperoxidationantioxidantsScienceQRUActa Biomedica Scientifica, Vol 3, Iss 6, Pp 23-28 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	adolescents reproductive health lipoperoxidation antioxidants Science Q
spellingShingle	adolescents reproductive health lipoperoxidation antioxidants Science Q N. A. Kurashova E. A. Kudeyarova Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups
description	Background. Processes of antioxidant protection in different ethnicities, living in the same geographical conditions, are of undoubted scientific interest. The ratio of activity of oxidative processes and antioxidant components not only reflects, but also largely determines the metabolism and adaptive capabilities of the organism. The key issue in understanding the regulatory and adaptive role of lipid peroxidation reactions in the body is the idea of the existence of a certain balance with the antioxidant defense system.Aims: to study the features of the system of lipid peroxidation and antioxidant protection in adolescents of different ethnicities, living in Eastern Siberia.Materials and methods. Parameters of lipid peroxidation and antioxidant protection were determined in the blood serum by spectrophotometric methods.Results. We found that adolescent Buryat boys had statistically significant decrease in primary and secondary products of lipid peroxidation: ketodienes and conjugated trienes, malondialdehyde, and components of antioxidant protection: retinol, α-tocopherol, the level of total antioxidant activity of blood and reduced glutathione, in comparison with Caucasian adolescents. In Caucasian adolescents with endocrine disorders, there was a statistically significant increase in the level of ketodienes and conjugated trienes, as well as the activity of superoxide dismutase against the background of a decrease of reduced glutathione, tocopherol, and retinol. We revealed a significant increase in the concentration of ketodienes and conjugated trienes and a decrease of the oxidized glutathione in adolescents with endocrine disorders in comparison with healthy adolescents of Buryat ethnicity.Conclusions. Studying of the processes of lipid peroxidation and antioxidant system of the organism can be used as an additional criterion for complex examination of practically healthy adolescents, which significantly enhance the representation about the adaptation possibilities of the organism to external conditions and can become a basis for effective examination of reproductive health in the future.
format	article
author	N. A. Kurashova E. A. Kudeyarova
author_facet	N. A. Kurashova E. A. Kudeyarova
author_sort	N. A. Kurashova
title	Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups
title_short	Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups
title_full	Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups
title_fullStr	Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups
title_full_unstemmed	Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups
title_sort	pro- and antioxidant activity in the blood of adolescents of different ethnic groups
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/85fa27e16778423f89b85b29f3a4a7eb
work_keys_str_mv	AT nakurashova proandantioxidantactivityinthebloodofadolescentsofdifferentethnicgroups AT eakudeyarova proandantioxidantactivityinthebloodofadolescentsofdifferentethnicgroups
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Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups

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