The structural basis for RNA selectivity by the IMP family of RNA-binding proteins

ZBP1 and IMP2 belong to the IGF2BP family of RNA-binding proteins. Here the authors employed SELEX, NMR spectroscopy and mutagenesis to characterize the RNA-binding preference of ZBP1 and IMP2.

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Autores principales:	Jeetayu Biswas, Vivek L. Patel, Varun Bhaskar, Jeffrey A. Chao, Robert H. Singer, Carolina Eliscovich
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/85ff9493a0c0443292b6df3d1c010479
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spelling	oai:doaj.org-article:85ff9493a0c0443292b6df3d1c0104792021-12-02T17:31:22ZThe structural basis for RNA selectivity by the IMP family of RNA-binding proteins10.1038/s41467-019-12193-72041-1723https://doaj.org/article/85ff9493a0c0443292b6df3d1c0104792019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12193-7https://doaj.org/toc/2041-1723ZBP1 and IMP2 belong to the IGF2BP family of RNA-binding proteins. Here the authors employed SELEX, NMR spectroscopy and mutagenesis to characterize the RNA-binding preference of ZBP1 and IMP2.Jeetayu BiswasVivek L. PatelVarun BhaskarJeffrey A. ChaoRobert H. SingerCarolina EliscovichNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jeetayu Biswas Vivek L. Patel Varun Bhaskar Jeffrey A. Chao Robert H. Singer Carolina Eliscovich The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
description	ZBP1 and IMP2 belong to the IGF2BP family of RNA-binding proteins. Here the authors employed SELEX, NMR spectroscopy and mutagenesis to characterize the RNA-binding preference of ZBP1 and IMP2.
format	article
author	Jeetayu Biswas Vivek L. Patel Varun Bhaskar Jeffrey A. Chao Robert H. Singer Carolina Eliscovich
author_facet	Jeetayu Biswas Vivek L. Patel Varun Bhaskar Jeffrey A. Chao Robert H. Singer Carolina Eliscovich
author_sort	Jeetayu Biswas
title	The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
title_short	The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
title_full	The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
title_fullStr	The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
title_full_unstemmed	The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
title_sort	structural basis for rna selectivity by the imp family of rna-binding proteins
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/85ff9493a0c0443292b6df3d1c010479
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The structural basis for RNA selectivity by the IMP family of RNA-binding proteins

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