Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications

The surface functionalisation of high-density polyethylene (HDPE) and HDPE/alumina-toughened zirconia (ATZ) surfaces with chitosan via electron-beam (EB) irradiation technique was exploited for preparing materials suitable for biomedical purposes. ATR–FTIR analysis and wettability measurements were...

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Autores principales:	Maria Giulia Faga, Donatella Duraccio, Mattia Di Maro, Christelle Kowandy, Giulio Malucelli, Federico Davide Mussano, Tullio Genova, Xavier Coqueret
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	high-density polyethylene (HDPE) alumina-toughened zirconia (ATZ) chitosan radiation-induced grafting electron-beam irradiation wettability Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/860c98180847422c9265876794f06f84
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spelling	oai:doaj.org-article:860c98180847422c9265876794f06f842021-11-25T18:49:28ZElectron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications10.3390/polym132240162073-4360https://doaj.org/article/860c98180847422c9265876794f06f842021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4360/13/22/4016https://doaj.org/toc/2073-4360The surface functionalisation of high-density polyethylene (HDPE) and HDPE/alumina-toughened zirconia (ATZ) surfaces with chitosan via electron-beam (EB) irradiation technique was exploited for preparing materials suitable for biomedical purposes. ATR–FTIR analysis and wettability measurements were employed for monitoring the surface changes after both irradiation and chitosan grafting reaction. Interestingly, the presence of ATZ loadings beyond 2 wt% influenced both the EB irradiation process and the chitosan functionalisation reaction, decreasing the oxidation of the surface and the chitosan grafting. The EB irradiation induced an increase in Young’s modulus and a decrease in the elongation at the break of all analysed systems, whereas the tensile strength was not affected in a relevant way. Biological assays indicated that electrostatic interactions between the negative charges of the surface of cell membranes and the –NH<sub>3</sub><sup>+</sup> sites on chitosan chains promoted cell adhesion, while some oxidised species produced during the irradiation process are thought to cause a detrimental effect on the cell viability.Maria Giulia FagaDonatella DuraccioMattia Di MaroChristelle KowandyGiulio MalucelliFederico Davide MussanoTullio GenovaXavier CoqueretMDPI AGarticlehigh-density polyethylene (HDPE)alumina-toughened zirconia (ATZ)chitosanradiation-induced graftingelectron-beam irradiationwettabilityOrganic chemistryQD241-441ENPolymers, Vol 13, Iss 4016, p 4016 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	high-density polyethylene (HDPE) alumina-toughened zirconia (ATZ) chitosan radiation-induced grafting electron-beam irradiation wettability Organic chemistry QD241-441
spellingShingle	high-density polyethylene (HDPE) alumina-toughened zirconia (ATZ) chitosan radiation-induced grafting electron-beam irradiation wettability Organic chemistry QD241-441 Maria Giulia Faga Donatella Duraccio Mattia Di Maro Christelle Kowandy Giulio Malucelli Federico Davide Mussano Tullio Genova Xavier Coqueret Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications
description	The surface functionalisation of high-density polyethylene (HDPE) and HDPE/alumina-toughened zirconia (ATZ) surfaces with chitosan via electron-beam (EB) irradiation technique was exploited for preparing materials suitable for biomedical purposes. ATR–FTIR analysis and wettability measurements were employed for monitoring the surface changes after both irradiation and chitosan grafting reaction. Interestingly, the presence of ATZ loadings beyond 2 wt% influenced both the EB irradiation process and the chitosan functionalisation reaction, decreasing the oxidation of the surface and the chitosan grafting. The EB irradiation induced an increase in Young’s modulus and a decrease in the elongation at the break of all analysed systems, whereas the tensile strength was not affected in a relevant way. Biological assays indicated that electrostatic interactions between the negative charges of the surface of cell membranes and the –NH<sub>3</sub><sup>+</sup> sites on chitosan chains promoted cell adhesion, while some oxidised species produced during the irradiation process are thought to cause a detrimental effect on the cell viability.
format	article
author	Maria Giulia Faga Donatella Duraccio Mattia Di Maro Christelle Kowandy Giulio Malucelli Federico Davide Mussano Tullio Genova Xavier Coqueret
author_facet	Maria Giulia Faga Donatella Duraccio Mattia Di Maro Christelle Kowandy Giulio Malucelli Federico Davide Mussano Tullio Genova Xavier Coqueret
author_sort	Maria Giulia Faga
title	Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications
title_short	Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications
title_full	Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications
title_fullStr	Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications
title_full_unstemmed	Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications
title_sort	electron-beam-induced grafting of chitosan onto hdpe/atz composites for biomedical applications
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/860c98180847422c9265876794f06f84
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Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications

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