A conformational switch in initiation factor 2 controls the fidelity of translation initiation in bacteria

A conformational switch in initiation factor 2 controls the fidelity of translation initiation in bacteria

The GTP-bound form of initiation factor 2 (IF2) promotes translation initiation by accelerating 50S ribosomal subunit joining the 30S ribosomal initiation complex (30S IC). Here the authors use single-molecule FRET and ensemble rapid kinetic methods to uncover the mechanism behind IF2-mediated subun...

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Autores principales: Kelvin Caban, Michael Pavlov, Måns Ehrenberg, Ruben L. Gonzalez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/860cc1998dec4bbfa9a56eec475500c0
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