Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
Antibodies (Abs) targeting highly conserved epitopes are important tools against emerging virus variants. Here, the authors characterize Abs that recognize a cryptic epitope in the receptor-binding domain of SARS-CoV-2 spike that is well conserved and show that these Abs can neutralize several varia...
Guardado en:
Autores principales: | Tingting Li, Wenhui Xue, Qingbing Zheng, Shuo Song, Chuanlai Yang, Hualong Xiong, Sibo Zhang, Minqing Hong, Yali Zhang, Hai Yu, Yuyun Zhang, Hui Sun, Yang Huang, Tingting Deng, Xin Chi, Jinjin Li, Shaojuan Wang, Lizhi Zhou, Tingting Chen, Yingbin Wang, Tong Cheng, Tianying Zhang, Quan Yuan, Qinjian Zhao, Jun Zhang, Jason S. McLellan, Z. Hong Zhou, Zheng Zhang, Shaowei Li, Ying Gu, Ningshao Xia |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/86208d0971bf4ed2a80bc56f650c0589 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus
por: Zhihai Li, et al.
Publicado: (2017) -
Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles
por: Daning Wang, et al.
Publicado: (2020) -
Luminescence properties of Eu2+ and Sm3+ co-doped in KBaPO4
por: Xu Yingwei, et al.
Publicado: (2021) -
Asymptotic stabilization of underactuated surface vehicles with actuator saturation
por: Pengfei Zhang, et al.
Publicado: (2021) -
Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity
por: Zhihai Li, et al.
Publicado: (2018)