CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality

The authors show that the CD200 receptor (CD200R) promotes effective clearance of pulmonary Francisella tularensis infection in knock out mice. This result is unexpected as CD200R is known to dampen pulmonary immune responses, and these data suggest that the beneficial effect against F. tularensis i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: J. Casulli, M. E. Fife, S. A. Houston, S. Rossi, J. Dow, E. D. Williamson, G. C Clark, T. Hussell, R. V. D’Elia, M. A Travis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/863531790019429fb219fb31b164b0b1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!