CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality

The authors show that the CD200 receptor (CD200R) promotes effective clearance of pulmonary Francisella tularensis infection in knock out mice. This result is unexpected as CD200R is known to dampen pulmonary immune responses, and these data suggest that the beneficial effect against F. tularensis i...

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Autores principales: J. Casulli, M. E. Fife, S. A. Houston, S. Rossi, J. Dow, E. D. Williamson, G. C Clark, T. Hussell, R. V. D’Elia, M. A Travis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/863531790019429fb219fb31b164b0b1
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