Monocytes from infliximab-resistant patients with Crohn’s disease exhibit a disordered cytokine profile

Abstract Crohn's disease (CD) is a chronic inflammatory disorder characterized by immune response dysregulation. Tumor necrosis factor-α (TNFα) is a key cytokine in the pathogenesis of CD, as indicated by the efficacy of anti-TNF-α therapy with infliximab (IFX). However, approximately 30–40% of...

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Autores principales: Federica Gaiani, Bianca Maria Rotoli, Francesca Ferrari, Amelia Barilli, Rossana Visigalli, Maria Clotilde Carra, Gian Luigi de’Angelis, Nicola de’Angelis, Valeria Dall’Asta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8636936dc86841a397cc30500d3d886e
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