Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

Psychiatric disorders are often accompanied by alterations in BMI and body composition due to changes in eating behaviour and physical activity. Here, Hübel et al. study the genetic overlap between these traits and find that genetic correlations between psychiatric disorders and body composition are...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Christopher Hübel, Héléna A. Gaspar, Jonathan R. I. Coleman, Ken B. Hanscombe, Kirstin Purves, Inga Prokopenko, Mariaelisa Graff, Julius S. Ngwa, Tsegaselassie Workalemahu, ADHD Working Group of the Psychiatric Genomics Consortium, Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC), Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, PTSD Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, International Headache Genetics Consortium, Paul F. O’Reilly, Cynthia M. Bulik, Gerome Breen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/863cf5db36a34aa2af52cbcbf3287303
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:863cf5db36a34aa2af52cbcbf3287303
record_format	dspace
spelling	oai:doaj.org-article:863cf5db36a34aa2af52cbcbf32873032021-12-02T15:35:47ZGenetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent10.1038/s41467-019-13544-02041-1723https://doaj.org/article/863cf5db36a34aa2af52cbcbf32873032019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13544-0https://doaj.org/toc/2041-1723Psychiatric disorders are often accompanied by alterations in BMI and body composition due to changes in eating behaviour and physical activity. Here, Hübel et al. study the genetic overlap between these traits and find that genetic correlations between psychiatric disorders and body composition are sex-specific and evident only in adulthood.Christopher HübelHéléna A. GasparJonathan R. I. ColemanKen B. HanscombeKirstin PurvesInga ProkopenkoMariaelisa GraffJulius S. NgwaTsegaselassie WorkalemahuADHD Working Group of the Psychiatric Genomics ConsortiumMeta-Analyses of Glucose and Insulin-related traits consortium (MAGIC)Autism Working Group of the Psychiatric Genomics ConsortiumBipolar Disorder Working Group of the Psychiatric Genomics ConsortiumEating Disorders Working Group of the Psychiatric Genomics ConsortiumMajor Depressive Disorder Working Group of the Psychiatric Genomics ConsortiumOCD & Tourette Syndrome Working Group of the Psychiatric Genomics ConsortiumPTSD Working Group of the Psychiatric Genomics ConsortiumSchizophrenia Working Group of the Psychiatric Genomics ConsortiumSex Differences Cross Disorder Working Group of the Psychiatric Genomics ConsortiumSubstance Use Disorders Working Group of the Psychiatric Genomics ConsortiumGerman Borderline Genomics ConsortiumInternational Headache Genetics ConsortiumPaul F. O’ReillyCynthia M. BulikGerome BreenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher Hübel Héléna A. Gaspar Jonathan R. I. Coleman Ken B. Hanscombe Kirstin Purves Inga Prokopenko Mariaelisa Graff Julius S. Ngwa Tsegaselassie Workalemahu ADHD Working Group of the Psychiatric Genomics Consortium Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC) Autism Working Group of the Psychiatric Genomics Consortium Bipolar Disorder Working Group of the Psychiatric Genomics Consortium Eating Disorders Working Group of the Psychiatric Genomics Consortium Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium PTSD Working Group of the Psychiatric Genomics Consortium Schizophrenia Working Group of the Psychiatric Genomics Consortium Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium Substance Use Disorders Working Group of the Psychiatric Genomics Consortium German Borderline Genomics Consortium International Headache Genetics Consortium Paul F. O’Reilly Cynthia M. Bulik Gerome Breen Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
description	Psychiatric disorders are often accompanied by alterations in BMI and body composition due to changes in eating behaviour and physical activity. Here, Hübel et al. study the genetic overlap between these traits and find that genetic correlations between psychiatric disorders and body composition are sex-specific and evident only in adulthood.
format	article
author	Christopher Hübel Héléna A. Gaspar Jonathan R. I. Coleman Ken B. Hanscombe Kirstin Purves Inga Prokopenko Mariaelisa Graff Julius S. Ngwa Tsegaselassie Workalemahu ADHD Working Group of the Psychiatric Genomics Consortium Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC) Autism Working Group of the Psychiatric Genomics Consortium Bipolar Disorder Working Group of the Psychiatric Genomics Consortium Eating Disorders Working Group of the Psychiatric Genomics Consortium Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium PTSD Working Group of the Psychiatric Genomics Consortium Schizophrenia Working Group of the Psychiatric Genomics Consortium Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium Substance Use Disorders Working Group of the Psychiatric Genomics Consortium German Borderline Genomics Consortium International Headache Genetics Consortium Paul F. O’Reilly Cynthia M. Bulik Gerome Breen
author_facet	Christopher Hübel Héléna A. Gaspar Jonathan R. I. Coleman Ken B. Hanscombe Kirstin Purves Inga Prokopenko Mariaelisa Graff Julius S. Ngwa Tsegaselassie Workalemahu ADHD Working Group of the Psychiatric Genomics Consortium Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC) Autism Working Group of the Psychiatric Genomics Consortium Bipolar Disorder Working Group of the Psychiatric Genomics Consortium Eating Disorders Working Group of the Psychiatric Genomics Consortium Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium PTSD Working Group of the Psychiatric Genomics Consortium Schizophrenia Working Group of the Psychiatric Genomics Consortium Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium Substance Use Disorders Working Group of the Psychiatric Genomics Consortium German Borderline Genomics Consortium International Headache Genetics Consortium Paul F. O’Reilly Cynthia M. Bulik Gerome Breen
author_sort	Christopher Hübel
title	Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
title_short	Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
title_full	Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
title_fullStr	Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
title_full_unstemmed	Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
title_sort	genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/863cf5db36a34aa2af52cbcbf3287303
work_keys_str_mv	AT christopherhubel geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT helenaagaspar geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT jonathanricoleman geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT kenbhanscombe geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT kirstinpurves geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT ingaprokopenko geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT mariaelisagraff geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT juliussngwa geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT tsegaselassieworkalemahu geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT adhdworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT metaanalysesofglucoseandinsulinrelatedtraitsconsortiummagic geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT autismworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT bipolardisorderworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT eatingdisordersworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT majordepressivedisorderworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT ocdtourettesyndromeworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT ptsdworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT schizophreniaworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT sexdifferencescrossdisorderworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT substanceusedisordersworkinggroupofthepsychiatricgenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT germanborderlinegenomicsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT internationalheadachegeneticsconsortium geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT paulforeilly geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT cynthiambulik geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent AT geromebreen geneticcorrelationsofpsychiatrictraitswithbodycompositionandglycemictraitsaresexandagedependent
_version_	1718386424531648512

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

Ejemplares similares