Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala

Activation of Thy-1 expressing neurons in the basolateral amygdala (BLA) has been shown to result in inhibition of fear. Here the authors present a comprehensive workflow to identify genes that are upregulated in this population and can be pharmacologically targeted to enable fear extinction.

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Autores principales: Kenneth M. McCullough, Dennis Choi, Jidong Guo, Kelsey Zimmerman, Jordan Walton, Donald G. Rainnie, Kerry J. Ressler
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8648cad174914c65a41baa622362e723
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spelling oai:doaj.org-article:8648cad174914c65a41baa622362e7232021-12-02T17:32:04ZMolecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala10.1038/ncomms131492041-1723https://doaj.org/article/8648cad174914c65a41baa622362e7232016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13149https://doaj.org/toc/2041-1723Activation of Thy-1 expressing neurons in the basolateral amygdala (BLA) has been shown to result in inhibition of fear. Here the authors present a comprehensive workflow to identify genes that are upregulated in this population and can be pharmacologically targeted to enable fear extinction.Kenneth M. McCulloughDennis ChoiJidong GuoKelsey ZimmermanJordan WaltonDonald G. RainnieKerry J. ResslerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kenneth M. McCullough
Dennis Choi
Jidong Guo
Kelsey Zimmerman
Jordan Walton
Donald G. Rainnie
Kerry J. Ressler
Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
description Activation of Thy-1 expressing neurons in the basolateral amygdala (BLA) has been shown to result in inhibition of fear. Here the authors present a comprehensive workflow to identify genes that are upregulated in this population and can be pharmacologically targeted to enable fear extinction.
format article
author Kenneth M. McCullough
Dennis Choi
Jidong Guo
Kelsey Zimmerman
Jordan Walton
Donald G. Rainnie
Kerry J. Ressler
author_facet Kenneth M. McCullough
Dennis Choi
Jidong Guo
Kelsey Zimmerman
Jordan Walton
Donald G. Rainnie
Kerry J. Ressler
author_sort Kenneth M. McCullough
title Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
title_short Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
title_full Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
title_fullStr Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
title_full_unstemmed Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
title_sort molecular characterization of thy1 expressing fear-inhibiting neurons within the basolateral amygdala
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/8648cad174914c65a41baa622362e723
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AT kelseyzimmerman molecularcharacterizationofthy1expressingfearinhibitingneuronswithinthebasolateralamygdala
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