Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors

Prion propagation can be interfered with by the expression of a second prion protein in the host. In the present study, we investigated prion propagation in a host expressing two different prion protein genes.

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Autores principales: Juan Carlos Espinosa, Olivier Andreoletti, Alba Marín-Moreno, Severine Lugan, Patricia Aguilar-Calvo, Hervé Cassard, Patricia Lorenzo, Jean-Yves Douet, Ana Villa-Díaz, Naima Aron, Irene Prieto, Alvina Huor, Juan María Torres
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/864be9f0adbd4cde9faed67640c7b37f
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spelling oai:doaj.org-article:864be9f0adbd4cde9faed67640c7b37f2021-11-03T18:56:09Z Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors 2150-751110.1128/mBio.03508-20https://doaj.org/article/864be9f0adbd4cde9faed67640c7b37f2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03508-20https://doaj.org/toc/2150-7511 Prion propagation can be interfered with by the expression of a second prion protein in the host. In the present study, we investigated prion propagation in a host expressing two different prion protein genes.Juan Carlos EspinosaOlivier AndreolettiAlba Marín-MorenoSeverine LuganPatricia Aguilar-CalvoHervé CassardPatricia LorenzoJean-Yves DouetAna Villa-DíazNaima AronIrene PrietoAlvina HuorJuan María TorresAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Juan Carlos Espinosa
Olivier Andreoletti
Alba Marín-Moreno
Severine Lugan
Patricia Aguilar-Calvo
Hervé Cassard
Patricia Lorenzo
Jean-Yves Douet
Ana Villa-Díaz
Naima Aron
Irene Prieto
Alvina Huor
Juan María Torres
Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors
description Prion propagation can be interfered with by the expression of a second prion protein in the host. In the present study, we investigated prion propagation in a host expressing two different prion protein genes.
format article
author Juan Carlos Espinosa
Olivier Andreoletti
Alba Marín-Moreno
Severine Lugan
Patricia Aguilar-Calvo
Hervé Cassard
Patricia Lorenzo
Jean-Yves Douet
Ana Villa-Díaz
Naima Aron
Irene Prieto
Alvina Huor
Juan María Torres
author_facet Juan Carlos Espinosa
Olivier Andreoletti
Alba Marín-Moreno
Severine Lugan
Patricia Aguilar-Calvo
Hervé Cassard
Patricia Lorenzo
Jean-Yves Douet
Ana Villa-Díaz
Naima Aron
Irene Prieto
Alvina Huor
Juan María Torres
author_sort Juan Carlos Espinosa
title Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors
title_short Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors
title_full Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors
title_fullStr Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors
title_full_unstemmed Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP <sup>C</sup> and Other Host-Specific Factors
title_sort allelic interference in prion replication is modulated by the convertibility of the interfering prp <sup>c</sup> and other host-specific factors
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/864be9f0adbd4cde9faed67640c7b37f
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