RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane

Assembly of filamentous RSV particles is incompletely understood due to a lack of techniques suitable for live-cell imaging. Here Vanover et al. use labeled soybean agglutinin to selectively label RSV G protein and show how filamentous RSV assembly, initiated in the cytoplasm, uses G protein recycle...

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Auteurs principaux: Daryll Vanover, Daisy V. Smith, Emmeline L. Blanchard, Eric Alonas, Jonathan L. Kirschman, Aaron W. Lifland, Chiara Zurla, Philip J. Santangelo
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/86556e99a50641d3ad241713d2b64c7f
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Résumé:Assembly of filamentous RSV particles is incompletely understood due to a lack of techniques suitable for live-cell imaging. Here Vanover et al. use labeled soybean agglutinin to selectively label RSV G protein and show how filamentous RSV assembly, initiated in the cytoplasm, uses G protein recycled from the plasma membrane.