Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons

Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons

Long noncoding RNAs (lncRNAs) are known to regulate the DNA damage response (DDR), however their role in the brain is less well studied. Here, the authors demonstrate a neuron-specific role for Brain Specific DNA-damage Related lncRNA1 (BS-DRL1) and show BS-DRL1 modulates DDR by interacting with HMG...

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Auteurs principaux: Min-Min Lou, Xiao-Qiang Tang, Guang-Ming Wang, Jia He, Fang Luo, Ming-Feng Guan, Fei Wang, Huan Zou, Jun-Ying Wang, Qun Zhang, Ming-Jian Xu, Qi-Li Shi, Li-Bing Shen, Guo-Ming Ma, Yi Wu, Yao-Yang Zhang, Ai-bin Liang, Ting-Hua Wang, Liu-Lin Xiong, Jian Wang, Jun Xu, Wen-Yuan Wang
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Science
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Accès en ligne:https://doaj.org/article/865a1ae8f53243eeaebf8820e40c99bb
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https://doaj.org/article/865a1ae8f53243eeaebf8820e40c99bb

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