Neuropeptides Involved in Facial Nerve Regeneration

Neuropeptides and neurotransmitters act as intermediaries to transmit impulses from one neuron to another via a synapse. These neuropeptides are also related to nerve degeneration and regeneration during nerve damage. Although there are various neuropeptides, three are associated with neural regener...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Inhyeok Kim, Yonjae Kim, Daewoong Kang, Junyang Jung, Sungsoo Kim, Hwasung Rim, Sanghoon Kim, Seung-Geun Yeo
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	neuropeptides facial nerve regeneration Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/866071f082ba49cab8e18e7f4ee55fed
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:866071f082ba49cab8e18e7f4ee55fed
record_format	dspace
spelling	oai:doaj.org-article:866071f082ba49cab8e18e7f4ee55fed2021-11-25T16:49:10ZNeuropeptides Involved in Facial Nerve Regeneration10.3390/biomedicines91115752227-9059https://doaj.org/article/866071f082ba49cab8e18e7f4ee55fed2021-10-01T00:00:00Zhttps://www.mdpi.com/2227-9059/9/11/1575https://doaj.org/toc/2227-9059Neuropeptides and neurotransmitters act as intermediaries to transmit impulses from one neuron to another via a synapse. These neuropeptides are also related to nerve degeneration and regeneration during nerve damage. Although there are various neuropeptides, three are associated with neural regeneration in facial nerve damage: calcitonin gene-related peptide (CGRP), galanin, and pituitary adenylyl cyclase-activating peptide (PACAP). Alpha CGRP in facial motoneurons is a signaling factor involved in neuroglial and neuromuscular interactions during regeneration. Thus, it may be a marker for facial nerve regeneration. Galanin is a marker of injured axons rather than nerve regeneration. PACAP has various effects on nerve regeneration by regulating the surrounding cells and providing neurotrophic factors. Thus, it may also be used as a marker for facial nerve regeneration. However, the precise roles of these substances in nerve generation are not yet fully understood. Animal studies have demonstrated that they may act as neuromodulators to promote neurotrophic factors involved in nerve regeneration as they appear early, before changes in the injured cells and their environment. Therefore, they may be markers of nerve regeneration.Inhyeok KimYonjae KimDaewoong KangJunyang JungSungsoo KimHwasung RimSanghoon KimSeung-Geun YeoMDPI AGarticleneuropeptidesfacial nerveregenerationBiology (General)QH301-705.5ENBiomedicines, Vol 9, Iss 1575, p 1575 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	neuropeptides facial nerve regeneration Biology (General) QH301-705.5
spellingShingle	neuropeptides facial nerve regeneration Biology (General) QH301-705.5 Inhyeok Kim Yonjae Kim Daewoong Kang Junyang Jung Sungsoo Kim Hwasung Rim Sanghoon Kim Seung-Geun Yeo Neuropeptides Involved in Facial Nerve Regeneration
description	Neuropeptides and neurotransmitters act as intermediaries to transmit impulses from one neuron to another via a synapse. These neuropeptides are also related to nerve degeneration and regeneration during nerve damage. Although there are various neuropeptides, three are associated with neural regeneration in facial nerve damage: calcitonin gene-related peptide (CGRP), galanin, and pituitary adenylyl cyclase-activating peptide (PACAP). Alpha CGRP in facial motoneurons is a signaling factor involved in neuroglial and neuromuscular interactions during regeneration. Thus, it may be a marker for facial nerve regeneration. Galanin is a marker of injured axons rather than nerve regeneration. PACAP has various effects on nerve regeneration by regulating the surrounding cells and providing neurotrophic factors. Thus, it may also be used as a marker for facial nerve regeneration. However, the precise roles of these substances in nerve generation are not yet fully understood. Animal studies have demonstrated that they may act as neuromodulators to promote neurotrophic factors involved in nerve regeneration as they appear early, before changes in the injured cells and their environment. Therefore, they may be markers of nerve regeneration.
format	article
author	Inhyeok Kim Yonjae Kim Daewoong Kang Junyang Jung Sungsoo Kim Hwasung Rim Sanghoon Kim Seung-Geun Yeo
author_facet	Inhyeok Kim Yonjae Kim Daewoong Kang Junyang Jung Sungsoo Kim Hwasung Rim Sanghoon Kim Seung-Geun Yeo
author_sort	Inhyeok Kim
title	Neuropeptides Involved in Facial Nerve Regeneration
title_short	Neuropeptides Involved in Facial Nerve Regeneration
title_full	Neuropeptides Involved in Facial Nerve Regeneration
title_fullStr	Neuropeptides Involved in Facial Nerve Regeneration
title_full_unstemmed	Neuropeptides Involved in Facial Nerve Regeneration
title_sort	neuropeptides involved in facial nerve regeneration
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/866071f082ba49cab8e18e7f4ee55fed
work_keys_str_mv	AT inhyeokkim neuropeptidesinvolvedinfacialnerveregeneration AT yonjaekim neuropeptidesinvolvedinfacialnerveregeneration AT daewoongkang neuropeptidesinvolvedinfacialnerveregeneration AT junyangjung neuropeptidesinvolvedinfacialnerveregeneration AT sungsookim neuropeptidesinvolvedinfacialnerveregeneration AT hwasungrim neuropeptidesinvolvedinfacialnerveregeneration AT sanghoonkim neuropeptidesinvolvedinfacialnerveregeneration AT seunggeunyeo neuropeptidesinvolvedinfacialnerveregeneration
_version_	1718412967722090496

Neuropeptides Involved in Facial Nerve Regeneration

Ejemplares similares