EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks

The exosome is a ribonucleolytic complex that plays part in RNA processing and degradation. Here, the authors reveal an RNA clearance event in homologous recombination and show the function of EXOSC10, a component of the exosome, in the homeostasis of RNA molecules synthesized at DSB sites.

Guardado en:
Detalles Bibliográficos
Autores principales: Judit Domingo-Prim, Martin Endara-Coll, Franziska Bonath, Sonia Jimeno, Rosario Prados-Carvajal, Marc R. Friedländer, Pablo Huertas, Neus Visa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/8660cb7f19ec4cacaf434de3f58eee41
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares