EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks
The exosome is a ribonucleolytic complex that plays part in RNA processing and degradation. Here, the authors reveal an RNA clearance event in homologous recombination and show the function of EXOSC10, a component of the exosome, in the homeostasis of RNA molecules synthesized at DSB sites.
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/8660cb7f19ec4cacaf434de3f58eee41 |
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