Retinal pigment epithelium tear after intravitreal aflibercept injection

Masaaki Saito, Mariko Kano, Kanako Itagaki, Yasuharu Oguchi, Tetsuju Sekiryu Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan Abstract: To report a case complicated with a retinal pigment epithelium (RPE) tear after intravitreal aflibercept injection. A...

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Autores principales:	Saito M, Kano M, Itagaki K, Oguchi Y, Sekiryu T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/867580707bc84d4aa70f92cd0fe6bc49
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spelling	oai:doaj.org-article:867580707bc84d4aa70f92cd0fe6bc492021-12-02T00:21:28ZRetinal pigment epithelium tear after intravitreal aflibercept injection1177-54671177-5483https://doaj.org/article/867580707bc84d4aa70f92cd0fe6bc492013-06-01T00:00:00Zhttp://www.dovepress.com/retinal-pigment-epithelium-tear-after-intravitreal-aflibercept-injecti-a13479https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Masaaki Saito, Mariko Kano, Kanako Itagaki, Yasuharu Oguchi, Tetsuju Sekiryu Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan Abstract: To report a case complicated with a retinal pigment epithelium (RPE) tear after intravitreal aflibercept injection. A 78-year-old man had deteriorated visual acuity in his left eye. Fluorescein angiography showed occult choroidal neovascularization. Optical coherence tomography showed a serous retinal detachment and fibrovascular pigment epithelial detachment. He was diagnosed as typical age-related macular degeneration associated with pigment epithelial detachment and treatment consisting of three consecutive monthly intravitreal injections of aflibercept was planned. A month after the initial injection, his visual acuity had not improved. The red-free photograph showed an area of RPE defect inferior to the fovea. The fundus autofluorescence, fluorescein angiography, and optical coherence tomography clearly demonstrated the presence of an RPE tear. A second injection of aflibercept was performed due to a remaining serous retinal detachment. Although this is a single case and RPE tears may occur as a spontaneous complication of age-related macular degeneration patients, the risk of a tear should be discussed when considering aflibercept treatment for typical age-related macular degeneration patients with pigment epithelial detachment as there might be a risk for developing an RPE tear. Keywords: age-related macular degeneration, aflibercept, pigment epithelial detachment, retinal pigment epithelium tearSaito MKano MItagaki KOguchi YSekiryu TDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1287-1289 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Saito M Kano M Itagaki K Oguchi Y Sekiryu T Retinal pigment epithelium tear after intravitreal aflibercept injection
description	Masaaki Saito, Mariko Kano, Kanako Itagaki, Yasuharu Oguchi, Tetsuju Sekiryu Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan Abstract: To report a case complicated with a retinal pigment epithelium (RPE) tear after intravitreal aflibercept injection. A 78-year-old man had deteriorated visual acuity in his left eye. Fluorescein angiography showed occult choroidal neovascularization. Optical coherence tomography showed a serous retinal detachment and fibrovascular pigment epithelial detachment. He was diagnosed as typical age-related macular degeneration associated with pigment epithelial detachment and treatment consisting of three consecutive monthly intravitreal injections of aflibercept was planned. A month after the initial injection, his visual acuity had not improved. The red-free photograph showed an area of RPE defect inferior to the fovea. The fundus autofluorescence, fluorescein angiography, and optical coherence tomography clearly demonstrated the presence of an RPE tear. A second injection of aflibercept was performed due to a remaining serous retinal detachment. Although this is a single case and RPE tears may occur as a spontaneous complication of age-related macular degeneration patients, the risk of a tear should be discussed when considering aflibercept treatment for typical age-related macular degeneration patients with pigment epithelial detachment as there might be a risk for developing an RPE tear. Keywords: age-related macular degeneration, aflibercept, pigment epithelial detachment, retinal pigment epithelium tear
format	article
author	Saito M Kano M Itagaki K Oguchi Y Sekiryu T
author_facet	Saito M Kano M Itagaki K Oguchi Y Sekiryu T
author_sort	Saito M
title	Retinal pigment epithelium tear after intravitreal aflibercept injection
title_short	Retinal pigment epithelium tear after intravitreal aflibercept injection
title_full	Retinal pigment epithelium tear after intravitreal aflibercept injection
title_fullStr	Retinal pigment epithelium tear after intravitreal aflibercept injection
title_full_unstemmed	Retinal pigment epithelium tear after intravitreal aflibercept injection
title_sort	retinal pigment epithelium tear after intravitreal aflibercept injection
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/867580707bc84d4aa70f92cd0fe6bc49
work_keys_str_mv	AT saitom retinalpigmentepitheliumtearafterintravitrealafliberceptinjection AT kanom retinalpigmentepitheliumtearafterintravitrealafliberceptinjection AT itagakik retinalpigmentepitheliumtearafterintravitrealafliberceptinjection AT oguchiy retinalpigmentepitheliumtearafterintravitrealafliberceptinjection AT sekiryut retinalpigmentepitheliumtearafterintravitrealafliberceptinjection
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Retinal pigment epithelium tear after intravitreal aflibercept injection

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